Laurent Bruno, Millon Antoine, Richer de Forges Marc, Artru Bernard, Lermusiaux Patrick
Clinique du Pré, Le Mans, France.
Ann Vasc Surg. 2012 Feb;26(2):205-12. doi: 10.1016/j.avsg.2011.07.020.
After distal bypass for limb salvage, persistence of large ischemic ulcers with exposure of tendons, joints, and bone and secondary graft exposure can lead to amputation, even though the bypass remains patent. Coverage of such defects using free flaps is too lengthy and complex for use in elderly patients. Although quick and simple, pedicled flaps are often considered to be contraindicated in patients with occlusive artery disease. The purpose of this study was to evaluate the outcome of pedicled flaps harvested after evaluation of revascularized territories on angiograms for coverage of tissue defects.
From 1994 to 2000, a total of 23 pedicled flap procedures were performed in 22 patients with a mean age of 75 years (range, 54-91 years). The distal anastomosis of the bypass was located on a tibial or pedal artery in 19 cases and on the popliteal artery in 4. The indication for flap placement was chronic ulcer in 7 cases, secondary graft exposure in 15, and open fracture with acute ischemia in 1. To be considered as usable, the flap had to be vascularized by a pedicle fed by the bypassed artery and have a rotational axis sufficient to cover the defect. Muscle flaps were used in 11 cases, fasciocutaneous flaps in 10, and fascial flaps in 2.
The flap procedures in this study led to primary healing in 17 cases, secondary healing in 4 cases, and failure due to necrosis in 2. Follow-up examination was carried out with Doppler ultrasonography at 1, 6, and 12 months and every 6 months thereafter. The mean follow-up period was 23 months (range, 3-5 years). Statistical analysis demonstrated bypass patency, limb salvage, and survival rates in agreement with those previously reported in the literature.
Our results suggest that pedicle flaps are feasible after distal bypass in patients with lower-extremity occlusive artery disease. This technique expands the indication for limb salvage with low morbidity.
在进行肢体挽救的远端旁路手术后,即使旁路仍保持通畅,存在大的缺血性溃疡且肌腱、关节和骨骼暴露以及继发移植物暴露的情况仍可能导致截肢。对于老年患者,使用游离皮瓣覆盖此类缺损过于冗长和复杂。尽管带蒂皮瓣快速且简单,但在患有闭塞性动脉疾病的患者中通常被认为是禁忌的。本研究的目的是评估在血管造影评估血运重建区域后切取带蒂皮瓣用于覆盖组织缺损的结果。
1994年至2000年,共对22例患者进行了23次带蒂皮瓣手术,患者平均年龄75岁(范围54 - 91岁)。旁路的远端吻合口位于胫动脉或足背动脉19例,位于腘动脉4例。皮瓣放置的指征为慢性溃疡7例,继发移植物暴露15例,开放性骨折伴急性缺血1例。若要被视为可用,皮瓣必须由绕过的动脉供血的蒂血管化,并且具有足以覆盖缺损的旋转轴。使用肌皮瓣11例,筋膜皮瓣10例,筋膜瓣2例。
本研究中的皮瓣手术导致17例一期愈合,4例二期愈合,2例因坏死失败。在术后1、6和12个月以及此后每6个月进行多普勒超声随访检查。平均随访期为23个月(范围3 - 5年)。统计分析表明旁路通畅率、肢体挽救率和生存率与先前文献报道一致。
我们的结果表明,对于下肢闭塞性动脉疾病患者,远端旁路术后带蒂皮瓣是可行的。该技术扩大了肢体挽救的指征,且发病率低。