Hannebicque-Montaigne K, Le Roc'h A, Launay D, Coulon C, Deruelle P, Langlois S
Service de gynécologie obstétrique, hôpital Jeanne-de-Flandre, centre hospitalier régional universitaire de Lille, université Lille 2, 59037 Lille, France.
Ann Fr Anesth Reanim. 2012 Mar;31(3):239-42. doi: 10.1016/j.annfar.2011.11.023. Epub 2012 Feb 3.
Haemophagocytic syndrome (HPS) results from an inappropriate stimulation of macrophages in bone marrow and lymphoid organs, leading to haemophagocytosis and hypercytokinemia. HPS may be primitive, essentially in pediatric population, or secondary to malignancy, infection or autoimmune disease. This disease is rare and prognosis is poor. A small number of cases during pregnancy have been described in literature. We report one HPS case in a pregnant patient at 21 week's gestation with systemic lupus erythematosus. We discuss diagnostic difficulties, obstetrical complications and therapeutic options.
噬血细胞综合征（HPS）是由骨髓和淋巴器官中巨噬细胞的不适当刺激引起的，导致噬血细胞增多和细胞因子血症。HPS可能是原发性的，主要见于儿童，或继发于恶性肿瘤、感染或自身免疫性疾病。这种疾病很罕见，预后很差。文献中描述了少数妊娠期间的病例。我们报告一例妊娠21周的系统性红斑狼疮孕妇发生HPS的病例。我们讨论了诊断困难、产科并发症和治疗选择。
