Department of Medicine, Division of Nephrology, University of Rochester, Rochester, NY, USA.
Am J Kidney Dis. 2012 Apr;59(4):550-7. doi: 10.1053/j.ajkd.2011.11.040. Epub 2012 Feb 2.
Although dialysis modality education is associated with higher rates of peritoneal dialysis (PD) use, some patients start hemodialysis (HD) therapy despite initially selecting PD as their modality of choice. This study seeks to identify predictors of this discrepancy.
Retrospective cohort study.
SETTING & PARTICIPANTS: 217 patients who received dialysis modality education at the University of Rochester between January 2004 and September 2009 and subsequently started dialysis therapy.
Demographic (age, race, sex, and timing of education), social (education, income, insurance, marital, employment, and smoking status), and clinical data (estimated glomerular filtration rate, cause of end-stage renal disease [ESRD], number of comorbid conditions, and number of nephrology visits).
HD use at initiation and day 91 of dialysis therapy in patients initially selecting PD.
Of 217 patients receiving education and starting dialysis therapy, at the time of education, 124 chose PD, 52 were undecided, and 41 chose HD. Modality distribution at the time of dialysis therapy initiation was 150 with HD and 67 with PD. Of 124 patients who chose PD at the time of education, 59 started dialysis therapy with PD and 65 started with HD. On day 91, a total of 60 patients were on PD therapy and 55 were on HD therapy. Nine patients had either died, undergone transplant, or not yet reached 91 days of dialysis therapy. On multivariable analysis, nonglomerular cause of ESRD, age older than 75 years, and not being employed predicted starting with HD therapy, whereas age older than 75 years, nonwhite race, and nonglomerular cause of ESRD predicted HD use at day 91.
Single-center observational study.
This study shows that patients choosing PD after dialysis education may not start with this modality and identifies several predictors of this mismatch. Further investigation into predictors of this discrepancy and strategies promoting a PD start in patients selecting this modality are warranted.
尽管透析方式教育与更高的腹膜透析(PD)使用率相关,但一些患者尽管最初选择 PD 作为首选方式,但仍开始血液透析(HD)治疗。本研究旨在确定这种差异的预测因素。
回顾性队列研究。
2004 年 1 月至 2009 年 9 月在罗切斯特大学接受透析方式教育并随后开始透析治疗的 217 名患者。
人口统计学因素(年龄、种族、性别和教育时机)、社会因素(教育程度、收入、保险、婚姻、就业和吸烟状况)和临床数据(估计肾小球滤过率、终末期肾病[ESRD]的病因、合并症数量和肾脏科就诊次数)。
在最初选择 PD 的患者中,起始 HD 使用率和第 91 天的 PD 使用率。
在接受教育并开始透析治疗的 217 名患者中,在教育时,124 名患者选择 PD,52 名患者未决定,41 名患者选择 HD。开始透析治疗时的治疗方式分布为 150 例 HD 和 67 例 PD。在教育时选择 PD 的 124 名患者中,59 名患者开始 PD 治疗,65 名患者开始 HD 治疗。第 91 天,共有 60 名患者接受 PD 治疗,55 名患者接受 HD 治疗。9 名患者死亡、接受移植或尚未接受 91 天的透析治疗。多变量分析显示,ESRD 的非肾小球病因、年龄大于 75 岁和未就业预测开始接受 HD 治疗,而年龄大于 75 岁、非白人种族和 ESRD 的非肾小球病因预测第 91 天的 HD 使用。
单中心观察性研究。
本研究表明,接受透析教育后选择 PD 的患者可能不会开始使用这种方式,并确定了这种不匹配的几个预测因素。需要进一步研究这种差异的预测因素以及促进选择这种方式的患者开始 PD 的策略。