Clouqueur E, Lucot J-P, Collinet P, Farine M-O, Kerdraon O, Poncelet E
Clinique de gynécologie-obstétrique, hôpital Jeanne-de-Flandre, 1, avenue Eugène-Avinée, 59037 Lille cedex, France.
Clinique de gynécologie-obstétrique, hôpital Jeanne-de-Flandre, 1, avenue Eugène-Avinée, 59037 Lille cedex, France.
Gynecol Obstet Fertil. 2014 Feb;42(2):84-91. doi: 10.1016/j.gyobfe.2011.08.003. Epub 2012 Feb 4.
To propose a therapeutic approach and follow-up of patients with atypical polypoid adenomyoma (APA) wishing to remain fertile.
We are presenting a retrospective study of eight APA cases.
Two patients immediately received radical treatment, and one patient had an endometrial thermocoagulation. The remaining five patients received a conservative treatment with ultrasound and hysteroscopic monitoring. Among them, two had full-term pregnancies, one is being treated for infertility, in one case, the APA disappeared after three hysteroscopy-curettages and macroprogestative treatment. Lastly, one of our patients died from an aggressive endometrioid ovarian bilateral tumour associated with an endometrial adenocarcinoma.
Radical treatment is necessary for cases of APA in women no longer wishing to remain fertile. For those wishing to remain fertile, we can offer a conservative treatment once they have been informed regarding the associated risk of relapse, degeneration, and ovarian lesions which necessitate stricter follow-up.
为希望保留生育能力的非典型息肉样腺肌瘤(APA)患者提出一种治疗方法及随访方案。
我们对8例APA病例进行了回顾性研究。
2例患者立即接受了根治性治疗,1例患者进行了子宫内膜热凝术。其余5例患者接受了超声及宫腔镜监测下的保守治疗。其中,2例患者足月妊娠,1例患者正在接受不孕症治疗,1例患者在3次宫腔镜刮宫及大剂量孕激素治疗后APA消失。最后,我们的1例患者死于与子宫内膜腺癌相关的侵袭性双侧卵巢子宫内膜样肿瘤。
对于不再希望保留生育能力的女性APA患者,根治性治疗是必要的。对于希望保留生育能力的患者,在告知其复发、恶变及卵巢病变的相关风险后,我们可以提供保守治疗,这需要更严格的随访。