Institut Curie, INSERM U1021, CNRS, UMR 3347, F-91405 Orsay, France.
Dev Biol. 2012 Jun 1;366(1):96-9. doi: 10.1016/j.ydbio.2012.01.016. Epub 2012 Jan 28.
Controling embryonic stem cell fate in vitro has been a major challenge in the past decade. Several protocols have been developed to obtain neural crest derivatives in culture, using more or less defined conditions. Here, we present various strategies used to date to obtain neural crest specification and the markers that can be used to identify human neural crest cells.
在过去的十年中，控制胚胎干细胞的体外命运一直是一个主要挑战。已经开发了几种方案来获得培养中的神经嵴衍生物，使用或多或少定义的条件。在这里，我们介绍了迄今为止用于获得神经嵴特化的各种策略，以及可用于鉴定人神经嵴细胞的标记物。
