Chkhotua A, Pantsulaia T, Managadze L
National Center of Urology, Tbilisi, Georgia.
Georgian Med News. 2011 Dec(201):10-4.
The health-related quality of life (HRQoL) concept is frequently applied for the assessment of surgical or other treatment modalities. We evaluated the HRQoL of 57 kidney donors and compared it to: 120 age and sex matched healthy individuals; and 52 patients who underwent nephrectomy due to renal tumor. The Short Form-36 (SF-36), Giessen Subjective Complaints List (GBB-24) and Zerssen's Mood Scale (Bf-S) questionnaires have been used for this purpose. The mean scores of different domains have been calculated for all three questionnaires and compared between the groups. In three out of eight SF-36 items ("Social function", "Bodily pain" and "Vitality") the donors scored significantly better than the controls and patients. In all five GBB-24 items the donors scored higher than the controls and patients. For the "Gastric complaints" the difference was significant. The mood analysis has shown significant differences between the groups in favour of the donors. The HRQoL of living kidney donors is not different from that of healthy subjects and significantly better than HRQoL of urological patients after nephrectomy. The HRQol of living kidney donors and healthy individuals is similar and better than HRQol of the patients operated due to the medical indications. Further prospective studies are needed to increase our knowledge of factors influencing HRQol of the living kidney donors and patients after nephrectomy.
健康相关生活质量（HRQoL）概念经常用于评估手术或其他治疗方式。我们评估了57名活体肾供者的健康相关生活质量，并将其与以下对象进行比较：120名年龄和性别匹配的健康个体；以及52名因肾肿瘤接受肾切除术的患者。为此使用了简明健康调查问卷（SF-36）、吉森主观症状清单（GBB-24）和泽尔森情绪量表（Bf-S）问卷。计算了所有三份问卷不同领域的平均得分，并在各组之间进行比较。在简明健康调查问卷的八个项目中的三个项目（“社会功能”、“身体疼痛”和“活力”）中，供者的得分显著高于对照组和患者。在吉森主观症状清单的所有五个项目中，供者的得分高于对照组和患者。在“胃部不适”方面，差异显著。情绪分析显示各组之间存在有利于供者的显著差异。活体肾供者的健康相关生活质量与健康受试者的无异，且显著优于肾切除术后泌尿外科患者的健康相关生活质量。活体肾供者和健康个体的健康相关生活质量相似，且优于因医疗指征接受手术的患者的健康相关生活质量。需要进一步开展前瞻性研究，以增加我们对影响活体肾供者和肾切除术后患者健康相关生活质量因素的了解。
