Tchkonia D, Vacharadze K, Shaishmelashvili G, Rtskhiladze S, Khelia Y, Pkhakadze Y
National Center for Tuberculosis and Lung Diseases, HELSY T.E. Ltd, Tbilisi, Georgia.
Georgian Med News. 2011 Dec(201):32-6.
The primary treatment of endobronchial tuberculosis complicated by bronchial stenosis is antituberculous chemotherapy. Surgical resection and bronchoplastic reconstruction has long been the standard treatment. However, bronchoscopic intervention is essential to restore the patency of the involved bronchus and controlling TB. To our best knowledge this is a first report of bronchial stenting in Georgian Republic. We performed this procedure in cooperation with interventional cardiologists from Cardiac Catheterization Laboratory "HELSY T.E." Ltd. which have wide experience in stenting manipulations. A 24-year-old woman, after treatment with antituberculous medications for pulmonary tuberculosis, suffered by cough, dyspnea, wheezing. CT scan showed stricture of the left main bronchus starting from bifurcation to the end and having a lumen diameter 2mm. Bronchoscopic examination revealed focal narrowing to pinhole size to the left main bronchus with severe fibrotic changes. We decided to perform endobronchial stenting. Under general anesthesia, balloon-expendable, metallic, non-covered stent (Medtronic) was inserted across the stenotic lesion and was expanded under the pressure of 9 atmospheres using Indeflator Perouse Medical. Bronchography, taken immediately after stent insertion, showed an expanded left main bronchus. Postoperatively the patient did well. Chest radiographs taken after 6 days demonstrating a fully expanded stent, mediastinal repositioning towards the midline and normal aeration of the left lung. Patient's dyspnea was much improved. The patient has now been asymptomatic for 3 months. In conclusion, this case describes a patient with a cicatrical post-TB bronchial stenosis that was effectively treated by bronchoscopic stenting, which is alternative to surgical resection thus avoiding unwarranted thoracotomies and providing quality of life.
支气管内膜结核合并支气管狭窄的主要治疗方法是抗结核化疗。手术切除和支气管成形重建长期以来一直是标准治疗方法。然而,支气管镜介入对于恢复受累支气管的通畅和控制结核病至关重要。据我们所知,这是格鲁吉亚共和国首例支气管支架置入术的报告。我们与“HELSY T.E.”有限公司心脏导管实验室的介入心脏病专家合作进行了该手术,他们在支架操作方面有丰富经验。一名24岁女性,在接受抗结核药物治疗肺结核后,出现咳嗽、呼吸困难、喘息症状。CT扫描显示左主支气管自分叉处至末端狭窄,管腔直径2mm。支气管镜检查发现左主支气管局部狭窄至针孔大小,并伴有严重纤维化改变。我们决定进行支气管内支架置入术。在全身麻醉下,将球囊扩张式金属裸支架(美敦力公司)穿过狭窄病变部位,并使用Indeflator Perouse Medical在9个大气压下进行扩张。支架置入后立即进行的支气管造影显示左主支气管扩张。术后患者恢复良好。术后6天拍摄的胸部X线片显示支架完全扩张,纵隔向中线重新定位,左肺通气正常。患者的呼吸困难明显改善。患者现已无症状3个月。总之,本病例描述了一名患有结核后瘢痕性支气管狭窄的患者,通过支气管镜支架置入术得到有效治疗,这是手术切除的替代方法,从而避免了不必要的开胸手术并提高了生活质量。