Dzhikiia G M, Mchedluri T T, Nikolaĭshvili M I, Zurabishvili Z A, Iordanishvili G S
Georgian Med News. 2011 Dec(201):52-5.
The aim of the research was to study toxic effect of lambda-cigalothrin, on quantitative contents of free amino acid in muscle, liver and in brain of fishes in r. Alazani. It was found that under the action of lambda-cigalothrin total amount of free amino acid in fish's tissue was increasing, contents of glycine, asparagine and glutamine acids, alanine and cysteine also increased. Increasing of glutamine and asparagines acids content in muscle and liver of fish goes with the dissimilation of other amino acids through the process of their deaminization by glutamate dehydrogenation system. Increasing the alanine content is indicative of reinforcement of transamination processes. Decrease of phenylalanine, valine, glycine and the other amino acids content is explained by reinforcement of amino acids catabolism in condition of pesticide load, as it occurs in condition of fishes' intoxication by phenols.
该研究的目的是研究高效氯氟氰菊酯对阿拉扎尼河鱼类肌肉、肝脏和大脑中游离氨基酸定量含量的毒性作用。研究发现,在高效氯氟氰菊酯的作用下,鱼类组织中游离氨基酸的总量增加,甘氨酸、天冬酰胺和谷氨酸、丙氨酸和半胱氨酸的含量也增加。鱼类肌肉和肝脏中谷氨酰胺和天冬酰胺酸含量的增加与其他氨基酸通过谷氨酸脱氢酶系统的脱氨过程异化有关。丙氨酸含量的增加表明转氨过程增强。苯丙氨酸、缬氨酸、甘氨酸和其他氨基酸含量的降低是由于在农药负荷条件下氨基酸分解代谢增强所致,就像鱼类酚类中毒时的情况一样。