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生活方式行为能否解释社会经济地位差异与全因死亡率、致命和非致命心血管事件之间的关系?来自法国和北爱尔兰 PRIME 研究中年男性的证据。

Do lifestyle behaviours explain socioeconomic differences in all-cause mortality, and fatal and non-fatal cardiovascular events? Evidence from middle aged men in France and Northern Ireland in the PRIME Study.

机构信息

Queen's University Belfast, Belfast, United Kingdom.

出版信息

Prev Med. 2012 Mar-Apr;54(3-4):247-53. doi: 10.1016/j.ypmed.2012.01.017. Epub 2012 Jan 28.

Abstract

OBJECTIVE

To examine the contribution of lifestyle behaviours to the socioeconomic gradient in all-cause mortality, and fatal and non-fatal cardiovascular events.

METHOD

10,600 men aged 50-59 years examined in 1991-1994 in Northern Ireland (NI) and France and followed annually for deaths and cardiovascular events for 10 years. Baseline smoking habit, physical activity, and fruit, vegetable, and alcohol consumption were assessed.

RESULTS

All lifestyle behaviours showed marked socioeconomic gradients for most indicators in NI and France, with the exception of percentage of alcohol consumers in NI and frequency of alcohol consumption in NI and France. At 10 years, there were 544 deaths from any cause and 440 fatal and non-fatal cardiovascular events. After adjustment for country and age, socioeconomic gradients were further adjusted for lifestyle behaviours. For total mortality, the median residual contribution of lifestyle behaviours was 28% and for cardiovascular incidence, 41%. When cardiovascular risk factors were considered in conjunction with lifestyle behaviours these percentages increased to 38% and 67% respectively.

CONCLUSION

Lifestyle behaviours contribute to the gradient in mortality and cardiovascular incidence between socioeconomic groups, particularly for cardiovascular incidence, but a substantial proportion of these differentials was not explained by lifestyle behaviours and cardiovascular risk factors.

摘要

目的

探讨生活方式行为对全因死亡率、致命和非致命心血管事件的社会经济梯度的影响。

方法

1991 年至 1994 年在北爱尔兰(NI)和法国对 10600 名 50-59 岁的男性进行了检查,并在 10 年内每年对死亡和心血管事件进行随访。基线吸烟习惯、身体活动以及水果、蔬菜和酒精摄入量均进行了评估。

结果

在 NI 和法国,除了 NI 中的酒精消费者比例和 NI 及法国的酒精消费频率外,所有生活方式行为在大多数指标上都表现出明显的社会经济梯度。10 年后,有 544 人死于任何原因,440 人死于致命和非致命性心血管事件。在调整了国家和年龄因素后,进一步对生活方式行为进行了社会经济梯度的调整。对于总死亡率,生活方式行为的中位数剩余贡献为 28%,对于心血管发病率,为 41%。当将心血管风险因素与生活方式行为一起考虑时,这两个百分比分别增加到 38%和 67%。

结论

生活方式行为导致了社会经济群体之间死亡率和心血管发病率的梯度差异,尤其是对于心血管发病率,但这些差异的很大一部分不能用生活方式行为和心血管风险因素来解释。

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