Department of Chemistry and Institute of Biomedical Science, Fudan University, Shanghai, China.
Chem Commun (Camb). 2012 Mar 11;48(21):2689-91. doi: 10.1039/c2cc17997k. Epub 2012 Feb 3.
An aptamer microarray was directly fabricated on a MALDI target plate for high-throughput insulin detection. High sensitivities were observed both in standard solutions (5 ng mL(-1), 0.86 nM) and serum sample (20 ng mL(-1), 3.4 nM). This method shows great promise in the field of biomarker detection.
适体微阵列被直接构建在 MALDI 靶板上，用于高通量胰岛素检测。在标准溶液（5ng/mL，0.86nM）和血清样本（20ng/mL，3.4nM）中均观察到了高灵敏度。该方法在生物标志物检测领域具有广阔的应用前景。
