早期恶性外周神经鞘瘤源于孤立性神经纤维瘤。
Early-stage malignant peripheral nerve sheath tumour arising from a solitary neurofibroma.
机构信息
Department of Diagnostic, Ehime University Graduate School of Medicine, Shitsukawa, Toon city, Japan.
出版信息
Br J Radiol. 2012 Feb;85(1010):e26-30. doi: 10.1259/bjr/55588872.
Abstract
We report a case of early-stage malignant peripheral nerve sheath tumour (MPNST) found in a solitary neurofibroma, and its CT and MRI findings. A 19-year-old male with no known history of a neurofibromatosis presented with a painless swelling in the left forearm. CT and MRI scans showed a well-circumscribed, intermuscular mass, which was 6.0 cm in diameter and contained a strongly enhanced 1.0 cm nodular structure with surrounding oedema. Peripheral nerve continuity with the mass was not seen. Histological evaluation proved the nodular structure was an MPNST component completely surrounded by neurofibroma. Following an excisional biopsy with wide margins, the patient was followed up for a year without treatment and no recurrence was observed.
摘要
我们报告了一例早期恶性外周神经鞘瘤（MPNST）在单发神经纤维瘤中发现的病例，并介绍了其 CT 和 MRI 表现。一名 19 岁男性，无已知神经纤维瘤病病史，左前臂出现无痛性肿胀。CT 和 MRI 扫描显示边界清楚的肌间肿块，直径 6.0cm，包含一个强化明显的 1.0cm 结节状结构，周围有水肿。未见肿块与周围神经连续性。组织学评估证实结节状结构是完全被神经纤维瘤包围的 MPNST 成分。行广泛边缘切除活检后，患者未接受治疗并随访 1 年，未见复发。
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