Hallucinogen actions on human brain revealed.
作者信息
Lee Hyeong-Min, Roth Bryan L
机构信息
Department of Pharmacology, Program in Neuroscience and Division of Chemical Biology and Medicinal Chemistry, and National Institute of Mental Health Psychoactive Drug Screening Program, University of North Carolina Chapel Hill Medical School, Chapel Hill, NC 27514, USA.
出版信息
Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1820-1. doi: 10.1073/pnas.1121358109. Epub 2012 Jan 30.
Abstract
摘要
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Psilocybin-induced deficits in automatic and controlled inhibition are attenuated by ketanserin in healthy human volunteers.色胺酮可减弱健康志愿者中致幻剂引起的自动和受控抑制缺陷。
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Htr2a Gene and 5-HT(2A) Receptor Expression in the Cerebral Cortex Studied Using Genetically Modified Mice.利用基因改造小鼠研究大脑皮质中的Htr2a基因和5-羟色胺（2A）受体表达
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Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior.致幻剂通过募集特定的皮质5-羟色胺（2A）受体介导的信号通路来影响行为。
Neuron. 2007 Feb 1;53(3):439-52. doi: 10.1016/j.neuron.2007.01.008.
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Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action.
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