Dermatology Unit, Department of Medicine, University Malaya, Kuala Lumpur, Malaysia.
Australas J Dermatol. 2012 Feb;53(1):81-3. doi: 10.1111/j.1440-0960.2011.00779.x. Epub 2011 Jun 9.
Methotrexate toxicity is known to cause erosions of existing psoriatic plaques, although rare. We describe two patients who developed painful ulcerated psoriatic plaques as an early presenting sign of methotrexate toxicity and review the risk factors associated with this manifestation.
甲氨蝶呤中毒已知可导致现有银屑病斑块的糜烂，尽管这种情况很少见。我们描述了两名患者出现疼痛性溃疡性银屑病斑块，这是甲氨蝶呤中毒的早期表现，并回顾了与这种表现相关的危险因素。
