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建立掺锗光纤作为近距离放射治疗的热释光剂量计。

Establishment of Ge-doped optical fibres as thermoluminescence dosimeters for brachytherapy.

作者信息

Issa Fatma, Abdul Rahman A T, Hugtenburg Richard P, Bradley David A, Nisbet Andrew

机构信息

Department of Physics, University of Surrey, and Department of Medical Physics, Royal Surrey County Hospital NHS Foundation Trust, Guildford, GU2 7XH, UK.

出版信息

Appl Radiat Isot. 2012 Jul;70(7):1158-61. doi: 10.1016/j.apradiso.2011.12.027. Epub 2012 Jan 18.

DOI:10.1016/j.apradiso.2011.12.027
PMID:22309632
Abstract

This study aims to establish the sensitive, ∼120 μm high spatial resolution, high dynamic range Ge-doped optical fibres as thermoluminescence (TL) dosimeters for brachytherapy dose distribution. This requires investigation to accommodate sensitivity of detection, both for the possibility of short range dose deposition from beta components as well as gamma/x-mediated dose. In-air measurements are made at distances close to radionuclide sources, evaluating the fall off in dose along the transverse axis of 133Ba and 60Co radioactive sources, at distances from 2 mm up to 20 mm from their midpoints. Measurements have been compared with Monte Carlo code DOSRZnrc simulations for photon-mediated dose only, agreement being obtained to within 3% and 1% for the 133Ba and 60Co sources, respectively. As such, in both cases it is determined that as intended, beta dose has been filtered out by source encapsulation.

摘要

本研究旨在将灵敏的、高度约为120μm的高空间分辨率、高动态范围的掺锗光纤用作近距离放射治疗剂量分布的热释光(TL)剂量计。这需要进行研究,以适应检测的灵敏度,既要考虑β成分短程剂量沉积的可能性,也要考虑γ/ x介导的剂量。在靠近放射性核素源的距离处进行空气中测量,评估沿133Ba和60Co放射源横轴的剂量衰减,距离其中心点2mm至20mm。测量结果仅与光子介导剂量的蒙特卡罗代码DOSRZnrc模拟进行了比较,133Ba和60Co源的一致性分别在3%和1%以内。因此,在这两种情况下都确定,如预期的那样,β剂量已通过源封装被滤除。

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A review of recent advances in optical fibre sensors for in vivo dosimetry during radiotherapy.放疗期间用于体内剂量测定的光纤传感器的最新进展综述。
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Physics-aspects of dose accuracy in high dose rate (HDR) brachytherapy: source dosimetry, treatment planning, equipment performance and in vivo verification techniques.高剂量率近距离放射治疗中剂量准确性的物理方面:源剂量测定、治疗计划、设备性能及体内验证技术
J Contemp Brachytherapy. 2012 Jun;4(2):81-91. doi: 10.5114/jcb.2012.29364. Epub 2012 Jun 30.