Fasmer Ole Bernt, Liao Hanbo, Huang Yong, Berle Jan Øystein, Wu Junxian, Oedegaard Ketil Joachim, Wik Gustav, Zhang Zhangjin
Department of Clinical Medicine, Section for Psychiatry, Faculty of Medicine and Dentistry, University of Bergen, Norway.
J Acupunct Meridian Stud. 2012 Feb;5(1):15-20. doi: 10.1016/j.jams.2011.11.002. Epub 2011 Dec 9.
To study the effect of acupuncture on heart rate variability (HRV) by using linear and non-linear methods of analysis.
40 patients were recruited consecutively, including patients with insomnia, stomachache, diarrhea, dizziness, cervical syndrome, lower back pain, gonarthritis, peripheral facial paralysis, post-traumatic organic brain syndrome and urinary retention. Different acupoint prescriptions were used, according to the textbook for 5-years' education on traditional Chinese medicine specialty, which is used in Chinese Universities. HRV was recorded before, during, and after acupuncture.
Acupuncture substantially reduced variability, causing a 41% reduction in the standard deviation. Using a Fourier analysis, the variances both in the low frequency (LF) and the high frequency (HF) ranges were markedly reduced, but the LF/HF ratio (an indication of sympatho-vagal balance) was not altered. The HR was unchanged. The sample entropy, which is a measure of the complexity of time series, was significantly increased (+35%).
Acupuncture produced a pattern of changes different from that seen in pathological conditions, where increased variability and reduced complexity is expected.
采用线性和非线性分析方法研究针刺对心率变异性（HRV）的影响。
连续招募40例患者，包括失眠、胃痛、腹泻、头晕、颈椎病、腰痛、膝关节炎、周围性面瘫、创伤后器质性脑综合征和尿潴留患者。根据中国大学使用的5年制中医专业教材，采用不同的穴位处方。在针刺前、针刺期间和针刺后记录HRV。
针刺显著降低了变异性，使标准差降低了41%。使用傅里叶分析，低频（LF）和高频（HF）范围内的方差均显著降低，但LF/HF比值（交感-迷走神经平衡的指标）未改变。心率未改变。样本熵是衡量时间序列复杂性的指标，显著增加（+35%）。
针刺产生的变化模式与病理状态下不同，病理状态下预期变异性增加和复杂性降低。
