肾小球疾病：狼疮性肾炎维持治疗的观点。
Glomerular disease: perspectives on maintenance therapy in lupus nephritis.
机构信息
Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Clinical Research Center, Room 5-2551, Bethesda, MD 20892, USA.
出版信息
Nat Rev Nephrol. 2012 Feb 7;8(3):136-8. doi: 10.1038/nrneph.2012.17.
Abstract
Maintenance immunosuppressive drug therapy is necessary to counter the propensity of lupus nephritis to relapse. Claims that mycophenolate mofetil might be the magic bullet for both induction and maintenance therapies merit critical reappraisal due to inconsistent evidence of the superiority of mycophenolate mofetil over azathioprine, as well as its inordinately greater cost.
摘要
维持免疫抑制药物治疗对于对抗狼疮肾炎的复发倾向是必要的。由于环孢素和霉酚酸酯在诱导和维持治疗方面的优势的证据不一致，以及霉酚酸酯费用过高，因此，环孢素可能是诱导和维持治疗的“灵丹妙药”的说法值得重新评估。
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