Graff-Iversen Sidsel, Gjesdal Knut, Jugessur Astanand, Myrstad Marius, Nystad Wenche, Selmer Randi, Thelle Dag S
Division of Epidemiology, Norwegian Institute of Public Health andInstitute of Community Health, University of Tromsø, Norway.
Tidsskr Nor Laegeforen. 2012 Feb 7;132(3):295-9. doi: 10.4045/tidsskr.11.0567.
Clinical practice and the results of some studies may indicate that physical exercise in the form of endurance training may influence the development of atrial fibrillation (AF). The aim of this paper is to evaluate the scientific background for the hypothesis that there is a connection between physical activity and AF.
This paper is a review article based on searches in PubMed on specific topics, limited to the period 1995 through March 2011. We found 17 original articles and three relatively recent reviews. Each was read by at least two of the authors and then discussed. Seven of the original articles were excluded for methodological reasons, and we therefore discuss the other ten.
We found support for the hypothesis that systematic high intensity endurance training such as running can increase the risk of AF, whereas the studies provide no evidence that less intensive physical exercise such as walking increases the risk. Several of the studies have methodological weaknesses.
Important questions remain unanswered. There is a need for more studies that can shed light on the connection between training intensity, total volume of intensive endurance training, age-related changes and AF. Studies that include women are also needed.
临床实践和一些研究结果可能表明,以耐力训练形式进行的体育锻炼可能会影响心房颤动(AF)的发生发展。本文旨在评估体育活动与心房颤动之间存在关联这一假说的科学依据。
本文是一篇综述文章,基于在PubMed上对特定主题的检索,检索时间段为1995年至2011年3月。我们找到了17篇原创文章和3篇近期综述。每篇文章至少由两位作者阅读并进行讨论。由于方法学原因,排除了7篇原创文章,因此我们讨论其余10篇。
我们发现有证据支持这样的假说,即系统的高强度耐力训练(如跑步)会增加心房颤动的风险,而研究并未提供证据表明低强度体育锻炼(如散步)会增加风险。其中几项研究存在方法学上的缺陷。
重要问题仍未得到解答。需要更多研究来阐明训练强度、高强度耐力训练的总量、与年龄相关的变化以及心房颤动之间的关联。还需要纳入女性的研究。