Yepes-Nuñez J J, Gómez-García C, Espinosa-Herrera Y, Cardona-Villa R
Servicio de Alergología, Grupo Académico de Alergología Clínica y Experimental (GACE), Universidad de Antioquia, Medellín, Colombia.
Allergol Immunopathol (Madr). 2012 Nov-Dec;40(6):379-84. doi: 10.1016/j.aller.2011.11.008. Epub 2012 Feb 7.
Allergic diseases are very common, with the estimated cumulative prevalence in Colombia for asthma and allergic rhinitis being 22.7% and 31.3% respectively, and with a clear upward trend. A major social as well as economic impact associated with allergic disease has been described. Because in Colombia there are no studies that assess the Health-Related Quality of Life (HRQOL) in allergic respiratory diseases, our aim is to describe the HRQOL in subjects with respiratory allergy and its association with clinical control variables.
A prospective descriptive study was conducted among 76 Colombian subjects with rhinitis and asthma/allergic rhinitis. In order to evaluate the HRQOL, the instruments Kidscreen-27 and SF-36 were applied. The scores obtained in the HRQOL fields were correlated with the following clinical variables: peak expiratory flow (PEF) and peak nasal inspiratory flow (PNIF).
In children, the better HRQL domain is present in the school environment (55.9) and the worst in psychological well-being (39.9). For adults the worst HRQL was found in the emotional function domain (55.6) while the physical function (81.7) had the best. There were no statistical differences between groups of asthma/allergic rhinitis and allergic rhinitis. Subjects with allergic asthma showed a strong correlation between the mental health domain and PEF values (r=-0717, p=0.046).
Mental health is more affected than physical health in Colombian subjects with respiratory allergy. There was a strong correlation between the mental health domain and the values of PEF in patients with asthma/allergic rhinitis.
过敏性疾病非常常见，据估计，哥伦比亚哮喘和过敏性鼻炎的累计患病率分别为22.7%和31.3%，且呈明显上升趋势。已有研究描述了过敏性疾病对社会和经济的重大影响。由于在哥伦比亚尚无评估过敏性呼吸道疾病患者健康相关生活质量（HRQOL）的研究，我们旨在描述呼吸道过敏患者的HRQOL及其与临床控制变量的关联。
对76名患有鼻炎和哮喘/过敏性鼻炎的哥伦比亚受试者进行了一项前瞻性描述性研究。为评估HRQOL，应用了儿童生活质量量表27项（Kidscreen-27）和简明健康调查问卷（SF-36）。在HRQOL各领域获得的分数与以下临床变量相关：呼气峰流速（PEF）和鼻吸气峰流速（PNIF）。
在儿童中，学校环境领域的HRQL状况最佳（55.9），心理健康领域最差（39.9）。对于成年人，情绪功能领域的HRQL最差（55.6），而身体功能领域最佳（81.7）。哮喘/过敏性鼻炎组和过敏性鼻炎组之间无统计学差异。过敏性哮喘患者的心理健康领域与PEF值之间存在强相关性（r=-0.717，p=0.046）。
在患有呼吸道过敏的哥伦比亚受试者中，心理健康比身体健康受到的影响更大。哮喘/过敏性鼻炎患者的心理健康领域与PEF值之间存在强相关性。
