Wang Wei-qun, Zhang Jin-song, Zhao Xiao-jin
Department of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Zhonghua Yan Ke Za Zhi. 2011 Oct;47(10):927-33.
To explore the postoperative visual acuity results of wavefront-guided LASIK with iris recognition for myopia or myopic astigmatism and the changes of higher-order aberrations and contrast sensitivity function (CSF).
Series of prospective case studies, 158 eyes (85 cases) of myopia or myopic astigmatism were divided into two groups: one group underwent wavefront-guided LASIK with iris recognition (iris recognition group); another group underwent wavefront-guided LASIK treatment without iris recognition through the limbus maring point (non-iris recognition group). To comparative analyze the postoperative visual acuity, residual refraction, the RMS of higher-order aberrations and CSF of two groups.
There was no statistical significance difference between two groups of the average uncorrected visual acuity (t = 0.039, 0.058, 0.898; P = 0.844, 0.810, 0.343), best corrected visual acuity (t = 0.320, 0.440, 1.515; P = 0.572, 0.507, 0.218), and residual refraction [spherical equivalent (t = 0.027, 0.215, 0.238; P = 0.869, 0.643, 0.626), spherical (t = 0.145, 0.117, 0.038; P = 0.704, 0.732, 0.845) and cylinder (t = 1.676, 1.936, 0.334; P = 0.195, 0.164, 0.563)] at postoperative 10 days, 1 month and 3 month. The security index of iris recognition group at postoperative 3 month was 1.06 and non-iris recognition group was 1.03; the efficacy index of iris recognition group is 1.01 and non-iris recognition group was 1.00. Postoperative 3 month iris recognition group 93.83% eyes and non-iris recognition group of 90.91% eyes spherical equivalent within ± 0.50 D (χ(2) = 0.479, P = 0.489), iris recognition group of 98.77% eyes and non-iris recognition group of 97.40% eyes spherical equivalent within ± 1.00 D (Fisher test, P = 0.613). There was no significance difference between the two groups of security, efficacy and predictability. Non-iris recognition group postoperative 1 month and postoperative 3 months 3-order order aberrations root mean square value (RMS) higher than the iris recognition group increased (t = 3.414, -2.870; P = 0.027, 0.045), in particular of coma; the general higher-order aberrations (t = 0.386, 1.132; P = 0.719, 0.321), 4-order aberrations (t = 0.808, 2.720; P = 0.464, 0.063), and 5-order aberrations (t = 0.148, -1.717; P = 0.890, 0.161) show no statistically significant difference. Three months after surgery, two groups have recovered at all spatial frequencies of CSF, iris recognition group at 3.0 c/d (t = 3.209, P = 0.002) and 6.0 c/d (t = 2.997, P = 0.004) spatial frequencies of CSF under mesopic condition was better than non-iris recognition group, glare contrast sensitivity function (GCSF) for 3.0 c/d (t = 3.423, P = 0.001) and 6.0 c/d (t = 6.986, P = 0.000) spatial frequencies under mesopic condition and 1.5 c/d (t = 9.839, P = 0.000) and 3.0 c/d (t = 7.367, P = 0.000) spatial frequencies under photopic condition in iris recognition group were better than non-iris recognition group, there were no significant difference between two groups at the other spatial frequencies.
Wavefront-guided LASIK with or without iris recognition both acquired better postoperative visual acuity, but in comparison with without iris recognition, wavefront-guided LASIK with iris recognition is efficient to reduce coma and enhance contrast sensitivity of postoperative.
探讨带虹膜识别的波前引导准分子原位角膜磨镶术（LASIK）治疗近视及近视散光的术后视力结果、高阶像差及对比敏感度函数（CSF）的变化。
系列前瞻性病例研究，将158眼（85例）近视或近视散光患者分为两组：一组行带虹膜识别的波前引导LASIK（虹膜识别组）；另一组行通过角膜缘标记点的不带虹膜识别的波前引导LASIK治疗（非虹膜识别组）。比较分析两组术后视力、残余屈光度、高阶像差均方根值及CSF。
两组术后10天、1个月及3个月时平均裸眼视力（t = 0.039，0.058，0.898；P = 0.844，0.810，0.343）、最佳矫正视力（t = 0.320，0.440，1.515；P = 0.572，0.507，0.218）及残余屈光度[等效球镜度（t = 0.027，0.215，0.238；P = 0.869，0.643，0.626）、球镜度（t = 0.145，0.117，0.038；P = 0.704，0.732，0.845）和柱镜度（t = 1. (此处原文有误，推测应该是1.676, 1.936, 0.334; P = 0.195, 0.164, 0.563) ] 比较，差异均无统计学意义。虹膜识别组术后3个月安全指数为1.06，非虹膜识别组为1.03；虹膜识别组疗效指数为1.01，非虹膜识别组为1.00。术后3个月虹膜识别组93.83%的眼等效球镜度在±0.50 D以内，非虹膜识别组为90.91%（χ(2) = 0.479，P = 0.489）；虹膜识别组98.77%的眼等效球镜度在±1.00 D以内，非虹膜识别组为97.40%（Fisher检验，P = 0.613）。两组安全性、疗效及可预测性差异均无统计学意义。非虹膜识别组术后1个月及3个月3阶像差均方根值（RMS）高于虹膜识别组，尤其彗差增加（t = 3.414， -2.870；P = 0.027，0.045）；总体高阶像差（t = 0.386，1.132；P = 0.719，0.321）、4阶像差（t = 0.808，2.720；P = 0.464，0.063）及5阶像差（t = 0.148， -1.717；P = 0.890，0.161）差异无统计学意义。术后3个月，两组CSF各空间频率均恢复，虹膜识别组在中亮度条件下3.0 c/d（t = 3.209，P = 0.002）和6.0 c/d（t = 2.997，P = 0.004）空间频率的CSF优于非虹膜识别组，虹膜识别组在中亮度条件下3.0 c/d（t = 3.423，P = 0.001）和6.0 c/d（t =
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