Watanuki A, Yokomori T, Taniguchi T, Iesato H, Takeyoshi I, Kawano K, Tomizawa N, Miyamoto Y, Emura I
Dept. of Surgery, Ojiya General Hospital.
Gan No Rinsho. 1990 Sep;36(11):2067-72.
An endocrine cell carcinoma is a carcinoid tumor that has an especially malignant prognosis. We herein report on 2 cases of a biliary endocrine cell carcinoma. Case 1 involved a 68 year old man manifesting a fever, jaundice, hepatomegaly and a ballooned gallbladder. After decreasing the jaundice by PTCD, an exploratory abdominal operation was performed. As a tumor was found at the papilla of Vater, a pancreaticoduodenectomy was done. Case 2 involved a 72 year old woman who was diagnosed as having a gallbladder tumor and cholelithiasis. She was given a cholecystectomy and a choledocholithotomy. These 2 cases had hepatic metastasis within a year and subsequently died. Procedurally, an endocrine cell carcinoma should be treated separately from classical carcinoid tumors.
内分泌细胞癌是一种预后特别凶险的类癌肿瘤。我们在此报告2例胆管内分泌细胞癌。病例1为一名68岁男性，表现为发热、黄疸、肝肿大和胆囊膨胀。经皮经肝胆道引流术减轻黄疸后，进行了剖腹探查手术。由于在十二指肠乳头发现肿瘤，遂行胰十二指肠切除术。病例2为一名72岁女性，被诊断患有胆囊肿瘤和胆石症。她接受了胆囊切除术和胆总管切开取石术。这2例患者在一年内发生肝转移，随后死亡。在治疗方法上，内分泌细胞癌应与经典类癌肿瘤分开治疗。
