Merdzhanov A, Damianov D, Aleksandrova A, Evtimov G
Vutr Boles. 1981;20(5):34-9.
In three successive papers the clinical, diagnostic and surgical possibilities of biliary tract carcinoma are discussed on the base of 119 patients, undergone operation at the Chair of Abdominal Surgery for the period 1952-1979: 52 (44%) with gallbladder carcinoma, 48 (40% with biliary ducts carcinoma and 19 (16%) with duodenal papilla carcinoma. The authors report that gallbladder carcinoma is most frequent - 4.4 per cent of all biliary operations. The ratio males: females is 1:3 and the highest number of the patients is over the age of 60. The diagnosis is usually made with 6 months later due to the atypical clinical picture, progressing under the mask of cholelithiasis, found in 70-100 per cent of the cases. That is the reason in 5 per cent of the cases that carcinoma involved the whole gallbladder, metastases and infiltration of the adjacent organs being frequent. Resectable proved to be only 9 patients, the mortality rate kept high. A complex diagnostics is recommended with present-day methods and early prophylactic cholecystectomy in case of calculosis.
在三篇连续的论文中,基于1952年至1979年期间在腹部外科进行手术的119例患者,讨论了胆道癌的临床、诊断和手术可能性:52例(44%)为胆囊癌,48例(40%)为胆管癌,19例(16%)为十二指肠乳头癌。作者报告称,胆囊癌最为常见,占所有胆道手术的4.4%。男女比例为1:3,患者中年龄最大的是60岁以上。由于临床表现不典型,通常在6个月后才能做出诊断,这种不典型表现以胆石症为幌子发展,在70%至100%的病例中可见。这就是5%的病例中癌累及整个胆囊的原因,转移和邻近器官浸润很常见。仅9例患者可切除,死亡率一直很高。建议采用当今的方法进行综合诊断,对于有结石病的情况应尽早进行预防性胆囊切除术。