Hwang N, Grimer R J, Carter S R, Tillman R M, Abudu A, Jeys L M
University Hospital Coventry Warwickshire, Clifford Bridge Road, Coventry, Warwickshire CV2 2DX, UK.
J Bone Joint Surg Br. 2012 Feb;94(2):265-9. doi: 10.1302/0301-620X.94B2.27536.
We reviewed our initial seven-year experience with a non-invasive extendible prosthesis in 34 children with primary bone tumours. The distal femur was replaced in 25 cases, total femur in five, proximal femur in one and proximal tibia in three. The mean follow-up was 44 months (15 to 86) and 27 patients (79%) remain alive. The prostheses were lengthened by an electromagnetic induction mechanism in an outpatient setting and a mean extension of 32 mm (4 to 80) was achieved without anaesthesia. There were lengthening complications in two children: failed lengthening in one and the formation of scar tissue in the other. Deep infection developed in six patients (18%) and local recurrence in three. A total of 11 patients required further surgery to the leg. Amputation was necessary in five patients (20%) and a two-stage revision in another. There were no cases of loosening, but two patients had implant breakage and required revision. The mean Musculoskeletal Tumor Society functional score was 85% (60% to 100%) at last known follow-up. These early results demonstrate that the non-invasive extendible prosthesis allows successful lengthening without surgical intervention, but the high incidence of infection is a cause for concern.
我们回顾了在34例原发性骨肿瘤患儿中使用非侵入性可延长假体的最初7年经验。25例患儿的股骨远端被置换,5例患儿的整个股骨被置换,1例患儿的股骨近端被置换,3例患儿的胫骨近端被置换。平均随访时间为44个月(15至86个月),27例患儿(79%)仍然存活。假体在门诊通过电磁感应机制延长,平均延长32毫米(4至80毫米),无需麻醉。有2例患儿出现延长并发症:1例延长失败,另1例形成瘢痕组织。6例患者(18%)发生深部感染,3例出现局部复发。共有11例患者需要对腿部进行进一步手术。5例患者(20%)需要截肢,另1例需要进行两阶段翻修手术。没有出现松动病例,但有2例患者的植入物发生断裂,需要进行翻修。在最后一次已知随访时,肌肉骨骼肿瘤学会的平均功能评分为85%(60%至100%)。这些早期结果表明,非侵入性可延长假体无需手术干预即可成功延长,但感染发生率较高令人担忧。