Department of Anesthesiology and Pain Medicine, School of Medicine, Ewha Womans University, Seoul, Korea.
Korean J Anesthesiol. 2012 Jan;62(1):73-8. doi: 10.4097/kjae.2012.62.1.73. Epub 2012 Jan 25.
Transfusion-related acute lung injury (TRALI) is one of the leading causes of transfusion-related morbidity and mortality. However, it is frequently not diagnosed and under-reported, which could result in inappropriate treatment. Diagnostic definition for TRALI consists of hypoxia and bilateral pulmonary edema occurring during or within 6 hours of a transfusion in the absence of cardiac failure or intravascular volume overload. Here, we report a fatal case, which resulted from under-recognition and misdiagnosis of TRALI occurring during transfusion with packed red blood cells during a bilateral total knee replacement.
输血相关性急性肺损伤(TRALI)是输血相关发病率和死亡率的主要原因之一。然而,它经常未被诊断和报告不足,这可能导致治疗不当。TRALI 的诊断定义包括在输血期间或输血后 6 小时内发生的缺氧和双侧肺水肿,而不存在心力衰竭或血容量超负荷。在这里,我们报告了一例致命病例,该病例是在双侧全膝关节置换术期间输注红细胞悬液时由于对 TRALI 的认识不足和误诊而导致的。