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双侧全膝关节置换术中发生的“可能的 TRALI”-病例报告-。

"Possible TRALI" developed during bilateral total knee arthroplasty replacement -A case report-.

机构信息

Department of Anesthesiology and Pain Medicine, School of Medicine, Ewha Womans University, Seoul, Korea.

出版信息

Korean J Anesthesiol. 2012 Jan;62(1):73-8. doi: 10.4097/kjae.2012.62.1.73. Epub 2012 Jan 25.

Abstract

Transfusion-related acute lung injury (TRALI) is one of the leading causes of transfusion-related morbidity and mortality. However, it is frequently not diagnosed and under-reported, which could result in inappropriate treatment. Diagnostic definition for TRALI consists of hypoxia and bilateral pulmonary edema occurring during or within 6 hours of a transfusion in the absence of cardiac failure or intravascular volume overload. Here, we report a fatal case, which resulted from under-recognition and misdiagnosis of TRALI occurring during transfusion with packed red blood cells during a bilateral total knee replacement.

摘要

输血相关性急性肺损伤(TRALI)是输血相关发病率和死亡率的主要原因之一。然而,它经常未被诊断和报告不足,这可能导致治疗不当。TRALI 的诊断定义包括在输血期间或输血后 6 小时内发生的缺氧和双侧肺水肿,而不存在心力衰竭或血容量超负荷。在这里,我们报告了一例致命病例,该病例是在双侧全膝关节置换术期间输注红细胞悬液时由于对 TRALI 的认识不足和误诊而导致的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5036/3272533/d3c165c70ba9/kjae-62-73-g001.jpg

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本文引用的文献

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[Unclear acute respiratory failure in a 64-year-old woman after coronary intervention].
Dtsch Med Wochenschr. 2010 Nov;135(45):2235-8. doi: 10.1055/s-0030-1267506. Epub 2010 Nov 2.
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Transfusion-related acute lung injury: definition and review.输血相关急性肺损伤:定义与综述
Crit Care Med. 2005 Apr;33(4):721-6. doi: 10.1097/01.ccm.0000159849.94750.51.
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Transfusion-related acute lung injury.输血相关急性肺损伤
Br J Haematol. 1999 May;105(2):322-9. doi: 10.1111/j.1365-2141.1999.01357.x.

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