Department of Ophthalmology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Korea.
Curr Eye Res. 2012 Apr;37(4):334-8. doi: 10.3109/02713683.2011.629070. Epub 2012 Feb 10.
To describe the association between retinal vessel caliber and risk factors for branch retinal vein occlusion (BRVO).
We included 10,890 participants who underwent a health checkup at Kangbuk Samsung Hospital between January 2006 and December 2006. BRVO was diagnosed from retinal photographs taken for both eyes. Retinal vascular caliber measurements were performed using a computer-assisted program. Risk factors were assessed based on a patient-answered questionnaire and laboratory investigations. Logistic regression analyses were performed to identify potential risk factors for BRVO.
The overall prevalence of BRVO was 0.8%. Among all BRVO patients, the mean central retinal artery equivalent (CRAE) was 142.59 µm (±14.63 µm), and the mean central retinal vein equivalent (CRVE) was 203.46 µm (±18.84 µm). The mean CRAE and CRVE of the control eyes were 148.15 µm (± 15.89 µm) and 211.12 µm (±18.54 µm), respectively. There were significant differences in mean CRAE and CRVE between the control group and the BRVO group (P < 0.05). Arterial hypertension was an important risk factor for BRVO (OR: 1.02 (1.01-1.03).
Eyes with BRVO had narrow CRAE and CRVE when compared with age- and gender-matched normal eyes. Generalized attenuation of retinal vessel caliber may be characteristic of eyes with BRVO. Emphasis on blood pressure control is needed for the prevention of BRVO.
描述视网膜血管管径与分支静脉阻塞（BRVO）危险因素之间的关系。
我们纳入了 2006 年 1 月至 2006 年 12 月期间在康伯斯三星医院接受健康检查的 10890 名参与者。双眼视网膜照片诊断为 BRVO。使用计算机辅助程序进行视网膜血管管径测量。根据患者回答的问卷和实验室检查评估危险因素。进行 logistic 回归分析以确定 BRVO 的潜在危险因素。
BRVO 的总患病率为 0.8%。在所有 BRVO 患者中，平均中央视网膜动脉等效值（CRAE）为 142.59 µm（±14.63 µm），平均中央视网膜静脉等效值（CRVE）为 203.46 µm（±18.84 µm）。对照组的平均 CRAE 和 CRVE 分别为 148.15 µm（±15.89 µm）和 211.12 µm（±18.54 µm）。对照组和 BRVO 组之间的平均 CRAE 和 CRVE 存在显著差异（P < 0.05）。高血压是 BRVO 的重要危险因素（OR：1.02（1.01-1.03））。
与年龄和性别匹配的正常眼相比，BRVO 眼的 CRAE 和 CRVE 较窄。视网膜血管口径普遍减弱可能是 BRVO 眼的特征。需要强调血压控制以预防 BRVO。
