Anikin V V, Ivanov A P
Klin Med (Mosk). 1990 Jul;68(7):67-70.
Transesophageal pacing used for sinus dysfunction detection in 103 patients has been assessed for informative appropriateness in design of the attendance policy and efficacy of outpatient chemotherapy. The response control by electrophysiological monitoring was performed in 22 patients with true sick sinus syndrome (group 1) and 27 ones with sinus dysfunction (group 2). The rest patients were not controlled objectively. Transesophageal pacing of 5 group 1 patients brought about indications for surgical treatment. For 8 patients the follow-up revealed evolution of the sinus vegetative dysfunction into organic lesion which required surgical intervention in one case. The effect of chemotherapy with sympathomimetic drugs in adequate doses tended to reduction with increasing duration of the follow-up. In those with true sick sinus syndrome this process ran more actively. Long-term chemotherapy for sinus dysfunction is found effective as it warrants appreciable improvement of sinoatrial conduction, outpatient therapy control by dynamic transesophageal pacing is objective and can be recommended as adequate.
对103例用于窦性功能障碍检测的经食管起搏,在门诊化疗的就诊策略设计和疗效方面进行了信息适宜性评估。对22例真性病态窦房结综合征患者(第1组)和27例窦性功能障碍患者(第2组)进行了电生理监测的反应控制。其余患者未进行客观控制。第1组5例患者经食管起搏产生了手术治疗指征。随访发现8例患者的窦性自主神经功能障碍演变为器质性病变,其中1例需要手术干预。随着随访时间延长,给予足量拟交感神经药物化疗的效果有降低趋势。在真性病态窦房结综合征患者中,这一过程更为明显。发现长期化疗对窦性功能障碍有效,因为它可使窦房传导有明显改善,通过动态经食管起搏进行门诊治疗控制是客观的,可作为适当方法推荐。