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在监狱人群中识别有极高患精神病风险的男性。

Identifying men at ultra high risk of psychosis in a prison population.

机构信息

King's College London, King's Health Partners, Institute of Psychiatry, De Crespigny Road, London, SE5 8AF, United Kingdom.

出版信息

Schizophr Res. 2012 Apr;136(1-3):1-6. doi: 10.1016/j.schres.2012.01.025. Epub 2012 Feb 12.

Abstract

BACKGROUND

The prevalence of psychotic disorders among prisoners is relatively high. We sought to investigate the prevalence of men who have a very high risk of developing psychosis in a prison population.

METHODS

The Prodromal Questionnaire - Brief Version (Loewy, Pearson, Vinogradov, Bearden and Cannon, 2011), was used to screen newly-arrived prisoners in a London prison for features associated with an increased risk of psychosis. Concurrent validity was evaluated using the Comprehensive Assessment for At Risk Mental State (Yung et al., 2005).

RESULTS

750 prisoners were screened and 301 were underwent further clinical assessment. 5% the total number of those screened met diagnostic criteria for the ARMS and 3% had recently developed a first episode of psychosis. Using endorsement of items that also caused distress, the PQ-B predicted an ARMS or a psychotic disorder with 90% sensitivity and 44% specificity.

CONCLUSIONS

The PQ-B is effective in identifying people who are vulnerable to developing psychosis in a prison population.

摘要

背景

囚犯中出现精神病障碍的比例相对较高。我们试图调查在囚犯群体中,具有极高患精神病风险的男性的患病率。

方法

采用前驱症状问卷-简式版(Loewy、Pearson、Vinogradov、Bearden 和 Cannon,2011),对伦敦一所监狱新入狱的囚犯进行筛查,以发现与精神病风险增加相关的特征。使用风险精神状态综合评估(Yung 等人,2005)来评估同时存在的有效性。

结果

对 750 名囚犯进行了筛查,其中 301 名接受了进一步的临床评估。筛查总人数的 5%符合 ARMS 的诊断标准,3%最近出现了首次精神病发作。使用导致困扰的项目的认可,PQ-B 预测 ARMS 或精神病障碍的敏感性为 90%,特异性为 44%。

结论

PQ-B 可有效识别监狱人群中易患精神病的人群。

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