Prout T E
Department of Medicine, Greater Baltimore Medical Center, Johns Hopkins University School of Medicine.
Md Med J. 1990 Oct;39(10):933-7.
The pathogenesis of IDDM and NIDDM indicates a distinct difference between these diseases. Viral illness is implicated in IDDM, linked with evidence for an immune deficiency. NIDDM is not linked to viral illness or autoimmunity but is highly influenced by the inheritance of a defect in insulin production.
胰岛素依赖型糖尿病(IDDM)和非胰岛素依赖型糖尿病(NIDDM)的发病机制表明了这两种疾病之间存在明显差异。病毒感染与IDDM的发病有关,同时有证据显示其与免疫缺陷有关。NIDDM与病毒感染或自身免疫无关,但受胰岛素分泌缺陷遗传因素的影响很大。