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比较年轻和老年胃癌患者的临床病理特征:一项荟萃分析。

Comparison of the clinicopathological characteristics of young and elderly patients with gastric carcinoma: a meta analysis.

机构信息

GI Division, Shanghai Jiao-Tong University School of Medicine, Renji Hospital, Shanghai Institute of Digestive Disease, Shanghai, China.

出版信息

J Surg Oncol. 2012 Sep 1;106(3):346-52. doi: 10.1002/jso.23004. Epub 2012 Feb 13.

DOI:10.1002/jso.23004
PMID:22331676
Abstract

To evaluate the relationship between age and clinicopathological characteristics in gastric carcinoma patients, we performed the meta-analysis based on nine retrospective clinical trials. Comparing elderly patients with young patients it showed lower male/female ratio, more diffuse GC, more Borrmann type IV, more poorly differentiated carcinoma, more peritoneal metastasis, less vascular invasion, fewer partial resections, and better 5-year survival rate. These particular age-related characteristics need to be further investigated.

摘要

为了评估胃癌患者年龄与临床病理特征之间的关系,我们对 9 项回顾性临床研究进行了荟萃分析。与年轻患者相比,老年患者的男女比例较低,弥漫型胃癌更多,Borrmann Ⅳ型更多,低分化癌更多,腹膜转移更多,血管侵犯更少,部分切除更少,5 年生存率更高。这些特定的与年龄相关的特征需要进一步研究。

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