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运动和久坐的仓鼠的体温节律及对热原的反应。

Body temperature rhythm and response to pyrogen in exercising and sedentary hamsters.

作者信息

Conn C A, Borer K T, Kluger M J

机构信息

Department of Kinesiology, University of Michigan, Ann Arbor 48109.

出版信息

Med Sci Sports Exerc. 1990 Oct;22(5):636-42. doi: 10.1249/00005768-199010000-00015.

DOI:10.1249/00005768-199010000-00015
PMID:2233203
Abstract

In this study, we tested the hypothesis that daily voluntary exercise results in a chronic elevation in core temperature in the female golden hamster. Temperature and activity were measured by biotelemetry. Hamsters ran 6-7 km per night (12:12 L:D) when permitted access to wheels. No running occurred during the light periods. During the 3rd wk of running, temperatures of exercising hamsters were significantly elevated by 0.5 degree C (P less than 0.001) during the dark period and by 0.3 degree C (P less than 0.003) during the light period compared with sedentary hamsters. Cessation of running removed the difference between groups, and resumption of running restored it. Both the injection of endotoxin and the psychological stress of cage switch resulted in similar peak temperatures in exercising and sedentary hamsters despite higher pre-treatment temperatures in the exercise group. We interpret these results to support the hypothesis that regular exercise may cause an upward resetting of the set-point for body temperature.

摘要

在本研究中,我们验证了这样一个假设:雌性金黄仓鼠每日进行自主运动会导致核心体温长期升高。通过生物遥测技术测量体温和活动情况。当仓鼠能够使用跑轮时,它们每晚跑6 - 7公里(光照与黑暗时间比为12:12)。在光照期间不发生跑步行为。在跑步的第3周,与 sedentary 仓鼠相比,运动仓鼠在黑暗期的体温显著升高0.5摄氏度(P < 0.001),在光照期升高0.3摄氏度(P < 0.003)。停止跑步消除了两组之间的差异,恢复跑步后差异又重新出现。尽管运动组在预处理时体温较高,但注射内毒素和更换笼子带来的心理应激在运动和 sedentary 仓鼠中导致了相似的体温峰值。我们对这些结果的解释是支持这样一个假设,即规律运动可能会导致体温设定点向上重置。 (注:原文中“sedentary”可能有误,推测应为“sedentary”,意为久坐不动的,这里暂按此翻译。)

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