Covert Douglas J, Henry Christopher R, Bhatia Sandeep K, Croskrey Jason, Sanchez Cecilia R, Han Dennis P
Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Arch Ophthalmol. 2012 Feb;130(2):186-9. doi: 10.1001/archopthalmol.2011.1378.
To compare 20-gauge standard pars plana vitrectomy (PPV) with transconjunctival cannulated PPV in the development of intraoperative retinal breaks and postoperative rhegmatogenous retinal detachments (RRDs) in a large series of patients undergoing PPV for macular pucker or macular hole.
This study was conducted at an academic tertiary care vitreoretinal practice in Milwaukee, Wisconsin. Patients undergoing 3-port PPV with standard 20-gauge instrumentation were compared with patients undergoing 3-port PPV with transconjunctival cannulated systems, including 20 gauge, 23 gauge, and 25 gauge, from January 1, 2003, through December 31, 2009. The main outcome measures were rates of intraoperative retinal breaks and postoperative RRD.
Four hundred twenty-six unique eyes met inclusion criteria. Fifty-four of 426 eyes (12.7%) were diagnosed as having new retinal tears intraoperatively as follows: 47 of 204 patients (23.0%) undergoing the standard 20-gauge procedure developed intraoperative retinal tears compared with 7 of 211 patients (3.3%) undergoing the transconjunctival cannulated procedure (risk ratio [RR], 0.12; 95% CI, 0.05-0.26; P < .001). Patients experiencing intraoperative retinal tears were not at increased risk of developing postoperative RRD (RR, 1.4; 95% CI, 0.39-5.0; P = .61). Although a trend was present, transconjunctival cannulated vitrectomy was not significantly protective against the development of postoperative RRD (RR, 0.60; 95% CI, 0.17-1.3; P = .14).
Transconjunctival cannulated PPV, including 20-gauge, 23-gauge, and 25-gauge systems, is associated with significantly reduced rates of intraoperative retinal tear formation compared with standard 20-gauge PPV.
在大量因黄斑皱襞或黄斑裂孔接受玻璃体切除术(PPV)的患者中,比较20号标准平坦部玻璃体切除术(PPV)与经结膜套针式PPV在术中视网膜裂孔形成及术后孔源性视网膜脱离(RRD)方面的情况。
本研究在威斯康星州密尔沃基市的一家学术性三级医疗玻璃体视网膜诊所进行。将使用标准20号器械进行三通道PPV的患者与使用经结膜套针系统(包括20号、23号和25号)进行三通道PPV的患者进行比较,研究时间为2003年1月1日至2009年12月31日。主要观察指标为术中视网膜裂孔发生率和术后RRD发生率。
426只眼符合纳入标准。426只眼中有54只(12.7%)在术中被诊断为出现新的视网膜裂孔,具体情况如下:204例接受标准20号手术的患者中有47例(23.0%)术中出现视网膜裂孔,而211例接受经结膜套针手术的患者中有7例(3.3%)出现术中视网膜裂孔(风险比[RR],0.12;95%可信区间[CI],0.05 - 0.26;P <.001)。术中出现视网膜裂孔的患者术后发生RRD的风险并未增加(RR,1.4;95%CI,0.39 - 5.0;P = 0.61)。尽管存在一种趋势,但经结膜套针式玻璃体切除术对术后RRD的发生并无显著的预防作用(RR,0.60;95%CI,0.17 - 1.3;P = 0.14)。
与标准20号PPV相比,包括20号、23号和25号系统在内的经结膜套针式PPV术中视网膜裂孔形成率显著降低。