[三萜糖苷与核酸嘌呤碱基分子络合的质谱分析]

[Mass spectrometry of triterpene glycosides molecular complexation with purine bases of nucleic acids].

作者信息

Lekar' A V, Vetrova E V, Borisenko N I, Iakovishin L A, Grishkovets V I

出版信息

Bioorg Khim. 2011 Sep-Oct;37(5):679-84. doi: 10.1134/s1068162011050116.

DOI:10.1134/s1068162011050116

Abstract

The molecular complexation of adenine and guanine with hederagenin 3-O-alpha-L-rhamnopyranosyl-(1-->2)-O-alpha-L-arabinopyranoside (alpha-hederin) and its 28-O-alpha-L-rhamnopyranosyl-(1-->4)-O-beta-D-glucopyranosyl-(1-->6)-O-beta-D-glucopyranosyl ester (hederasaponin C) was investigated for the first time using the method of electrospray ionization mass spectrometry. Guanine forms complexes more diverse in composition than adenine.

摘要

首次采用电喷雾电离质谱法研究了腺嘌呤和鸟嘌呤与常春藤皂苷元3 - O-α-L-鼠李吡喃糖基-(1→2)-O-α-L-阿拉伯吡喃糖苷（α-常春藤皂苷）及其28 - O-α-L-鼠李吡喃糖基-(1→4)-O-β-D-吡喃葡萄糖基-(1→6)-O-β-D-吡喃葡萄糖基酯（常春藤皂苷C）的分子络合作用。鸟嘌呤形成的络合物在组成上比腺嘌呤更为多样。