Ege University, Faculty of Science, Department of Chemistry, Bornova, Izmir, Turkey.
Phytochemistry. 2010 Apr;71(5-6):663-8. doi: 10.1016/j.phytochem.2009.12.001. Epub 2010 Jan 6.
Four triterpene saponins, agrostemmosides A-D were isolated from the methanol extract of Agrostemma gracilis. The structures of the compounds were determined as 3-O-beta-D-xylopyranosyloleanolic acid 28-O-beta-D-glucopyranosyl-(1-->2)-[beta-D-xylopyranosyl-(1-->6)]-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester, 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-xylopyranosyloleanolic acid 28-O-beta-D-glucopyranosyl-(1-->2)-[beta-D-xylopyranosyl-(1-->6)]-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester, 3-O-beta-D-xylopyranosylechinocystic acid 28-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester, 3-O-beta-D-xylopyranosylechinocystic acid 28-O-beta-D-glucopyranosyl-(1-->2)-[beta-D-xylopyranosyl-(1-->6)]-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester by a combination of one- and two-dimensional NMR techniques, and mass spectrometry. To the best of our knowledge this is the first phytochemical report on A. gracilis, and echinocystic acid saponins were encountered for the first time in Caryophyllaceae family.
从 Agrostemma gracilis 的甲醇提取物中分离得到四种三萜皂苷，命名为 agrostemmosides A-D。通过一维和二维 NMR 技术以及质谱联用等方法确定了它们的结构，分别为 3-O-β-D-吡喃木糖基齐墩果酸 28-O-β-D-吡喃葡萄糖基-(1-->2)-[β-D-吡喃木糖基-(1-->6)]-β-D-吡喃葡萄糖基-(1-->6)-β-D-吡喃葡萄糖基酯、3-O-α-L-鼠李吡喃糖基-(1-->2)-β-D-吡喃木糖基齐墩果酸 28-O-β-D-吡喃葡萄糖基-(1-->2)-[β-D-吡喃木糖基-(1-->6)]-β-D-吡喃葡萄糖基-(1-->6)-β-D-吡喃葡萄糖基酯、3-O-β-D-吡喃木糖基羽扇豆酸 28-O-β-D-吡喃葡萄糖基-(1-->2)-β-D-吡喃葡萄糖基-(1-->6)-β-D-吡喃葡萄糖基酯、3-O-β-D-吡喃木糖基羽扇豆酸 28-O-β-D-吡喃葡萄糖基-(1-->2)-[β-D-吡喃木糖基-(1-->6)]-β-D-吡喃葡萄糖基-(1-->6)-β-D-吡喃葡萄糖基酯。据我们所知，这是首次对 A. gracilis 进行植物化学研究，并且首次在石竹科中发现羽扇豆酸皂苷。
