氯胺酮相关性角膜水肿。
Ketamine-associated corneal edema.
机构信息
Save Sight Institute, University of Sydney, Sydney, Australia.
出版信息
Cornea. 2012 May;31(5):572-4. doi: 10.1097/ICO.0b013e31823f8af4.
PURPOSE
To report a case of ketamine-associated corneal edema.
METHODS
Case report.
RESULTS
A 61-year-old man prescribed oral ketamine for refractory depression developed bilateral corneal edema. This immediately resolved off ketamine and recurred with rechallenge. Rapid corneal endothelial cell loss occurred during this period.
CONCLUSIONS
Ketamine may induce potentially reversible corneal edema with endothelial cell loss. A thorough medication history of this and other drugs should be sought in patients with an otherwise unexplained corneal endothelial failure.
目的
报告 1 例氯胺酮相关性角膜水肿病例。
方法
病例报告。
结果
一位 61 岁男性因难治性抑郁症开了口服氯胺酮，随后出现双侧角膜水肿。停用氯胺酮后水肿立即消退，但再次使用时又复发了。在此期间，角膜内皮细胞迅速丢失。
结论
氯胺酮可能引起潜在可恢复的角膜水肿伴内皮细胞丢失。对于原因不明的角膜内皮功能衰竭患者，应仔细询问此类药物和其他药物的用药史。
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