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[青光眼性视盘的最重要体征]

[The most important signs of a glaucomatous disc].

作者信息

Mardin C Y

机构信息

Ophthalmologie, Universität Erlangen-Nürnberg, Erlangen.

出版信息

Klin Monbl Augenheilkd. 2012 Feb;229(2):112-8. doi: 10.1055/s-0031-1299127. Epub 2012 Feb 14.

Abstract

Glaucomatous optic atrophy is the result of both primary and secondary glaucomas leading to functional defects. Loss of axons and ganglion cells leads to a specific atrophy of the optic nerve head. Increased cup size and depth with loss of neuroretinal rim tissue are accompanied by changes of the retinal vessels and juxtapapillary retinal pigment epithelium. Changes of the retinal nerve fibre layer, caused by ganglion cell loss may be earliest signs of glaucomatous atrophy. The marked variability of optic disc size and form may influence the quality of ophthalmoscopic evaluation in extreme variants. Peripapillary haemorrhages and changes of pulsation properties of the retinal venules may give prognostic information for the course of the disease. These signs may be evaluated and even semiquantitatively measured with limited technical effort. They lay the basis for the evaluation of modern imaging and measuring techniques. This article summarises criteria described by Jonas and other authors in the light of modern imaging techniques and adds the latest scientific results.

摘要

青光眼性视神经萎缩是原发性和继发性青光眼导致功能缺陷的结果。轴突和神经节细胞的丧失导致视神经乳头的特定萎缩。杯盘比增大、深度增加以及神经视网膜边缘组织丧失,同时伴有视网膜血管和视乳头周围视网膜色素上皮的改变。神经节细胞丧失引起的视网膜神经纤维层变化可能是青光眼性萎缩的最早迹象。视盘大小和形态的显著变异性可能会影响极端变异情况下检眼镜评估的质量。视乳头周围出血和视网膜小静脉搏动特性的改变可为疾病进程提供预后信息。这些体征通过有限的技术手段即可进行评估甚至半定量测量。它们为现代成像和测量技术的评估奠定了基础。本文根据现代成像技术总结了约纳斯及其他作者描述的标准,并补充了最新的科学成果。

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