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[青光眼视乳头内和视乳头旁改变的相关性——对200只正常眼和450只青光眼眼的平面测量研究]

[Correlation of intra- and para-papillary glaucomatous changes--a planimetric study of 200 normal and 450 glaucoma eyes].

作者信息

Jonas J B, Gusek G C, Naumann G O

出版信息

Fortschr Ophthalmol. 1989;86(2):95-8.

PMID:2737578
Abstract

The zone "alpha" (irregular hypo- und hyperpigmentation) and "beta" (visible large choroidal vessels and visible sclera) of parapapillary chorioretinal atrophy had been measured in 450 eyes of 330 patients suffering from chronic primary open-angle glaucoma and in 200 normal eyes of 161 subjects. In the present study, the results were correlated with intrapapillary and other parapapillary parameters. Significant correlations (p less than 0.001) were found with: (1) the neuroretinal rim size; (2) the horizontal and vertical cup/disc ratios and the quotient; (3) the frequency of bared circumlinear and cilioretinal vessels and of optic disc hemorrhages, respectively; (4) the retinal vessel diameter; (5) the visibility of the retinal nerve fiber bundles; (6) the glaucoma stage. The parapapillary changes were most marked in the sector in which the neuroretinal rim notch was the largest and the narrowness of the retinal vessel caliber the most pronounced. The parapapillary glaucomatous changes in time and location correlated with the intrapapillary and other parapapillary alterations. They deserve special attention in the diagnosis of glaucoma.

摘要

在330例慢性原发性开角型青光眼患者的450只眼中以及161名受试者的200只正常眼中,对视乳头周围脉络膜视网膜萎缩的“α区”(不规则色素减退和色素沉着过多)和“β区”(可见粗大脉络膜血管和可见巩膜)进行了测量。在本研究中,将结果与视乳头内及其他视乳头周围参数进行了关联分析。发现与以下各项存在显著相关性(p<0.001):(1)神经视网膜边缘大小;(2)水平和垂直杯盘比及比值;(3)裸露的环行和睫状视网膜血管以及视盘出血的频率;(4)视网膜血管直径;(5)视网膜神经纤维束的可见性;(6)青光眼分期。视乳头周围改变在神经视网膜边缘切迹最大且视网膜血管口径狭窄最明显的象限最为显著。视乳头周围青光眼性改变在时间和位置上与视乳头内及其他视乳头周围改变相关。它们在青光眼的诊断中值得特别关注。

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