Sayani Raza, Ali Muhammad, Shazlee Kashif, Hamid Rana Shoaib, Hamid Kamran
Radiology Department, Aga Khan University Hospital, Karachi, Pakistan.
Int J Nephrol Renovasc Dis. 2012;5:15-21. doi: 10.2147/IJNRD.S27628. Epub 2011 Dec 30.
To determine the role of duplex Doppler ultrasonography (DDU) in patients with acute unilateral renal obstruction.
A total of 161 patients with suspected renal colic due to urolithiasis were evaluated by DDU followed by intravenous urography (IVU). The mean intra-arterial resistive index (RI) and the difference of mean resistive index between both kidneys (delta RI) were determined for each person. An RI value of ≥0.70 and a delta RI value of ≥0.06 were taken as the discriminatory threshold for obstruction. IVU results were considered the " reference standard" against which renal DDU findings were compared.
IVU showed both kidneys to be normal in 51 patients and with unilateral ureteric obstruction in 110 patients. The mean RI for obstructed kidneys was 0.67 (0.048), which was significantly higher (P-value <0.05) than a mean RI of contralateral normal kidneys 0.59 (0.04). The mean delta RI in patients with unilateral ureteric obstruction was significantly higher than that in patients with normal kidneys, at 0.076 (0.03) and 0.03 (0.05), respectively. In patients with complete obstruction, sensitivity of RI and delta RI were 77.5% and 92.5% with a specificity of 84.3% and 90.1%, respectively. In patients with partial obstruction, the sensitivity of these values was 22.8% and 62.8% with a specificity of 84.3% and 90.1%.
Delta RI is more sensitive and specific than RI in acute renal obstruction. However, due to relatively low sensitivity for detection of partial obstruction, DDU cannot replace IVU as the standard imaging technique.
确定双功多普勒超声检查(DDU)在急性单侧肾梗阻患者中的作用。
对161例疑似因尿路结石导致肾绞痛的患者进行了DDU检查,随后进行静脉尿路造影(IVU)。测定了每个人的平均动脉内阻力指数(RI)以及双肾之间的平均阻力指数差值(δRI)。RI值≥0.70和δRI值≥0.06被用作梗阻的鉴别阈值。IVU结果被视为与肾DDU检查结果进行比较的“参考标准”。
IVU显示51例患者双肾正常,110例患者存在单侧输尿管梗阻。梗阻肾的平均RI为0.67(0.048),明显高于对侧正常肾的平均RI 0.59(0.04)(P值<0.05)。单侧输尿管梗阻患者的平均δRI明显高于双肾正常患者,分别为0.076(0.03)和0.03(0.05)。在完全梗阻患者中,RI和δRI的敏感性分别为77.5%和92.5%,特异性分别为84.3%和90.1%。在部分梗阻患者中,这些值的敏感性分别为22.8%和62.8%,特异性分别为84.3%和90.1%。
在急性肾梗阻中,δRI比RI更敏感且更具特异性。然而,由于检测部分梗阻的敏感性相对较低,DDU不能取代IVU作为标准成像技术。