Tirkey Naveen Kumar, Mandavi Sanjay, Gupta Shashank
Department of Medicine, Pt. JNM Medical College and Dr. BR Ambedkar Memorial Hospital, Raipur - 492002, Chattisgarh.
J Assoc Physicians India. 2011 Sep;59:583-5.
Neuromyelitis optica, a variant of multiple sclerosis, presenting with hypocalcemic tetany is an unusual presentation. We report here a case of 25 years old female who was a case of neuromyelitis optica and had hypocalcemic tetany as the initial presentation among others. The case is interesting in that the hypocalcemic tetany was not coincidental. The patient had low vitamin D status and probably, this was correlated etiologically to neuromyelitis optica. Vitamin D has immunomodulatory effect and low vitamin D status has been implicated in the etiology of autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, insulin-dependent diabetes mellitus, and inflammatory bowel disease.
视神经脊髓炎是多发性硬化的一种变异型，以低钙性手足搐搦为表现较为罕见。我们在此报告一例25岁女性，她患有视神经脊髓炎，最初表现为低钙性手足搐搦等症状。该病例有趣之处在于低钙性手足搐搦并非偶然。患者维生素D水平较低，这可能在病因上与视神经脊髓炎相关。维生素D具有免疫调节作用，维生素D水平低与自身免疫性疾病如多发性硬化、类风湿关节炎、胰岛素依赖型糖尿病和炎症性肠病的病因有关。
