Jasti V Ramanamma Children's Eye Care Centre, L.V. Prasad Eye Institute, Hyderabad, India.
Am J Ophthalmol. 2012 Jul;154(1):13-19.e2. doi: 10.1016/j.ajo.2011.11.031. Epub 2012 Feb 14.
To assess the accuracy of IOL power calculation formulae in children less than 2 years of age.
Retrospective, comparative study, comprising of 128 eyes of 84 children.
We analyzed records of children less than 2 years with congenital cataract who underwent primary IOL implantation. Data were analyzed for prediction error using the 4 commonly used IOL power calculation formulae. We calculated the absolute prediction error with each of the formulae and the formula that gave least variability was determined. The formula that gave the best prediction error was determined.
Mean age at surgery was 11.7 ± 6.2 months. Absolute prediction error was found to be 2.27 ± 1.69 diopters (D) with SRK II, 3.23 ± 2.24 D with SRK T, 3.62 ± 2.42 D with Holladay, and 4.61 ± 3.12 D with Hoffer Q. The number of eyes with absolute prediction error within 0.5 D was 27 (21.1%) with SRK II, 8 (6.3%) with SRK T, 12 (9.4%) with Holladay, and 5 (3.9%) with Hoffer Q. Comparison between different formulae showed that the absolute prediction error with SRK II formula was significantly better than with other formulae (P < .001). Prediction error with SRK II formula was not affected by any factor such as age (P = .31), keratometry (P = .32), and axial length (P = .27) of the patient. Axial length influenced the absolute prediction error with Holladay (P = .05) and Hoffer Q formulae (P = .002). Mean keratometry influenced prediction error (P = .03) with SRK T formula.
Although absolute prediction error tends to remain high with all present IOL power calculation formulae, SRK II was the most predictable formula in our series.
评估小于 2 岁儿童的人工晶状体（IOL）计算公式的准确性。
回顾性比较研究，共纳入 84 例 128 只眼的患儿。
分析行初次 IOL 植入术的先天性白内障小于 2 岁患儿的病历资料。使用 4 种常用的 IOL 计算公式分析预测误差，计算各公式的绝对预测误差，确定变异性最小的公式。确定预测误差最小的公式。
手术时的平均年龄为 11.7±6.2 个月。SRK II 公式的绝对预测误差为 2.27±1.69 屈光度（D），SRK T 公式为 3.23±2.24 D，Holladay 公式为 3.62±2.42 D，Hoffer Q 公式为 4.61±3.12 D。绝对预测误差在 0.5 D 以内的眼数分别为：SRK II 公式 27 只（21.1%），SRK T 公式 8 只（6.3%），Holladay 公式 12 只（9.4%），Hoffer Q 公式 5 只（3.9%）。不同公式之间的比较显示，SRK II 公式的绝对预测误差明显优于其他公式（P<0.001）。SRK II 公式的预测误差不受患者年龄（P=0.31）、角膜曲率（P=0.32）和眼轴（P=0.27）等因素的影响。眼轴长度影响 Holladay（P=0.05）和 Hoffer Q 公式的绝对预测误差（P=0.002）。平均角膜曲率影响 SRK T 公式的预测误差（P=0.03）。
虽然所有目前的 IOL 计算公式的绝对预测误差仍较高，但在本系列中，SRK II 公式是最可预测的公式。
Zotero 插件