Han Zhen-ge, Liu Chun-xing, Pan Jie, Zhao Lan-jing, Wang Jie-li
Huadong Sanatorium, Wuxi 214065, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2011 Dec;45(12):1099-102.
To examine the prevalence changes of diabetes mellitus (DM) and impaired fasting glucose (IFG) from 2003 to 2010 in the health check-up subjects in Shanghai.
Health check-up subjects were divided into ten groups by sex and each 5 years old, and the prevalence of crude DM, crude IFG were calculated first. According to Chinese sex and age structure of China Population Statistics Yearbook 2006, sex and age standardized DM and standardized IFG were computed.
In the same year, the prevalences of crude DM and IFG increased with increasing age for both male and female, reached the summit at 60 - 69 age group, when at ≥ 70 age group, they had a down trend and were still at higher level. The prevalences of crude DM were 3.99% (986/24 699) in male and 1.61% (176/10 948) in female in 2003, and were 7.85% (3366/42 899) and 2.55% (531/20 820) in 2010. The prevalences of crude IFG were 9.97% (2462/24 699) in male and 5.88% (644/10 948) in female in 2003, and were 30.96% (13 283/42 899) and 17.16% (3573/20 820) in 2010. The prevalences of age standardized DM in 2003 and 2010 were 3.89% and 6.90% for male (χ(2) = 371.89, P < 0.01), 2.12% and 3.23% for female (χ(2) = 29.32, P < 0.01), respectively. The prevalences of age standardized IFG in 2003 and 2010 were 9.51% and 28.55% (χ(2) = 3865.56, P < 0.01) for male, 6.97% and 17.88% (χ(2) = 790.81, P < 0.01) for female. The prevalences of age and sex standardized DM were 3.00% and 5.05% (χ(2) = 385.39, P < 0.01), and prevalences of age and sex standardized IFG were 8.23% and 23.17% (χ(2) = 4480.21, P < 0.01).
From 2003 to 2010, prevalences of DM and IFG had increased greatly. It concluded that first-level prevention of DM for health check-up subjects should start from youth, and should lay emphasis on population of IFG, especially for male.
探讨2003年至2010年上海市健康体检人群中糖尿病（DM）和空腹血糖受损（IFG）的患病率变化情况。
将健康体检人群按性别及每5岁一组分为10组，首先计算DM粗患病率、IFG粗患病率。根据《中国人口统计年鉴2006》的中国性别和年龄结构，计算性别和年龄标准化的DM患病率及标准化IFG患病率。
同年，男性和女性的DM粗患病率和IFG粗患病率均随年龄增长而升高，在60 - 69岁年龄组达到高峰，≥70岁年龄组呈下降趋势，但仍处于较高水平。2003年男性DM粗患病率为3.99%（986/24 699），女性为1.61%（176/10 948）；2010年男性为7.85%（3366/42 899），女性为2.55%（531/20 820）。2003年男性IFG粗患病率为9.97%（2462/24 699），女性为5.88%（644/10 948）；2010年男性为30.96%（13 283/42 899），女性为17.16%（3573/20 820）。2003年和2010年男性年龄标准化DM患病率分别为3.89%和6.90%（χ(2)=371.89，P<0.01），女性分别为2.12%和3.23%（χ(2)=29.32，P<0.01）。2003年和2010年男性年龄标准化IFG患病率分别为9.51%和28.55%（χ(2)=3865.56，P<0.01），女性分别为6.97%和17.88%（χ(2)=790.81，P<0.01）。年龄和性别标准化的DM患病率分别为3.00%和5.05%（χ(2)=385.39，P<0.01），年龄和性别标准化的IFG患病率分别为8.23%和23.17%（χ(2)=4480.21，P<0.01）。
2003年至2010年，DM和IFG患病率大幅上升。得出结论，健康体检人群DM的一级预防应从青年时期开始，应重点关注IFG人群，尤其是男性。
