Duan Liu-fa, Ye Ping, Zheng Yan-song, Zhang Li-ping, Wang Fu-lin
Second Department of Cardiology, Southern Building Clinic Division, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2011 Nov;39(11):1021-3.
To analyze the clinic-pathologic features of elderly myocardial infarction patients (> 60 years) with and without left ventricular aneurysm formation.
Between January 1980 and October 2009, 107 myocardial infarction patients were divided into aneurysm group (n = 31) and non-aneurysm group (n = 76) according to autopsy results and the clinic-pathologic features of the two groups were compared.
Previous angina pectoris history was significantly less in aneurysm group than in non-aneurysm group [45.2% (14/31) vs. 92.1% (70/76), P = 0.047]. Incidence of hypertension was significantly higher in aneurysm group than in non-aneurysm group [77.4% (24/31) vs. 36.8% (28/76), P = 0.033]. The percentage of single-vessel disease [54.8% (17/31) vs. 23.7% (18/76), P = 0.033] and the LAD disease [96.8% (30/31) vs. 51.3% (39/76), P = 0.048] were both significantly higher in aneurysm group than in non-aneurysm group. Heart failure and ventricular arrhythmias were more likely the cause of death in patients with aneurysm than patients without aneurysm [56.3% (18/31) vs. 19.7% (15/76), P = 0.007]. Aneurysm mostly located in left ventricular anterior wall and apex.
Our results suggest that patients with left ventricular aneurysm formation are more likely to have hypertension, single-vessel disease and LAD disease, heart failure and ventricular arrhythmias but less previous angina pectoris than patients without left ventricular aneurysm formation. The common locations of ventricular aneurysm formation were left ventricular anterior wall and apex.
分析老年心肌梗死患者（>60岁）有无左心室室壁瘤形成的临床病理特征。
1980年1月至2009年10月，107例心肌梗死患者根据尸检结果分为室壁瘤组（n = 31）和非室壁瘤组（n = 76），比较两组的临床病理特征。
室壁瘤组既往心绞痛病史显著少于非室壁瘤组[45.2%（14/31）对92.1%（70/76），P = 0.047]。室壁瘤组高血压发病率显著高于非室壁瘤组[77.4%（24/31）对36.8%（28/76），P = 0.033]。单支血管病变百分比[54.8%（17/31）对23.7%（18/76），P = 0.033]和左前降支病变[96.8%（30/31）对51.3%（39/76），P = 0.048]在室壁瘤组均显著高于非室壁瘤组。与无室壁瘤患者相比，室壁瘤患者因心力衰竭和室性心律失常死亡的可能性更大[56.3%（18/31）对19.7%（15/76），P = 0.007]。室壁瘤大多位于左心室前壁和心尖部。
我们的结果表明，与无左心室室壁瘤形成的患者相比，有左心室室壁瘤形成的患者更易患高血压、单支血管病变和左前降支病变、心力衰竭和室性心律失常，但既往心绞痛病史较少。室壁瘤形成的常见部位是左心室前壁和心尖部。
