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Am J Respir Crit Care Med. 2012 Feb 15;185(4):460-1; author reply 461. doi: 10.1164/ajrccm.185.4.460.
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DNA methylation in the arginase-nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma.精氨酸酶-一氧化氮合酶通路中的 DNA 甲基化与哮喘患儿呼出气一氧化氮相关。
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Unmasking Pediatric Asthma: Epigenetic Fingerprints and Markers of Respiratory Infections.揭开儿童哮喘的面纱：表观遗传指纹与呼吸道感染标志物
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Epigenetic regulation: the interface between prenatal and early-life exposure and asthma susceptibility.表观遗传调控：产前和生命早期暴露与哮喘易感性之间的界面。
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Epigenetic mechanisms and the development of asthma.表观遗传学机制与哮喘的发生发展。
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本文引用的文献

1
DNA methylation in the arginase-nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma.精氨酸酶-一氧化氮合酶通路中的 DNA 甲基化与哮喘患儿呼出气一氧化氮相关。
Am J Respir Crit Care Med. 2011 Jul 15;184(2):191-7. doi: 10.1164/rccm.201012-2029OC. Epub 2011 Apr 21.
2
Fractional exhaled nitric oxide exchange parameters among 9-year-old inner-city children.9 岁城市内儿童呼出气一氧化氮交换参数的分数。
Pediatr Pulmonol. 2011 Jan;46(1):83-91. doi: 10.1002/ppul.21328. Epub 2010 Sep 16.
3
Increase in exhaled nitric oxide is associated with bronchial hyperresponsiveness among apprentices.呼出气一氧化氮增加与学徒的支气管高反应性有关。
Am J Respir Crit Care Med. 2010 Sep 15;182(6):738-44. doi: 10.1164/rccm.200903-0415OC. Epub 2010 May 27.
4
Effect of elevated exhaled nitric oxide levels on the risk of respiratory tract illness in preschool-aged children with moderate-to-severe intermittent wheezing.呼出一氧化氮水平升高对中重度间歇性喘息学龄前儿童呼吸道疾病风险的影响。
Ann Allergy Asthma Immunol. 2009 Aug;103(2):108-13. doi: 10.1016/S1081-1206(10)60162-7.
5
Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium.吸烟引起的支气管气道基因表达变化在鼻和颊黏膜上皮中也有体现。
BMC Genomics. 2008 May 30;9:259. doi: 10.1186/1471-2164-9-259.
6
Exhaled nitric oxide predicts asthma relapse in children with clinical asthma remission.呼出一氧化氮可预测临床哮喘缓解的儿童哮喘复发。
Thorax. 2005 Mar;60(3):215-8. doi: 10.1136/thx.2004.023374.

Bronchial nitric oxide flux may be better associated with inducible nitric oxide synthase promoter methylation.

作者信息

Kuriakose Julie, Rosa Maria José, Perzanowski Matthew, Miller Rachel

出版信息

Am J Respir Crit Care Med. 2012 Feb 15;185(4):460-1; author reply 461. doi: 10.1164/ajrccm.185.4.460.

DOI:10.1164/ajrccm.185.4.460
PMID:22336683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5448623/
Abstract
摘要