University of Medicine and Pharmacy Iuliu Hatieganu, Cluj-Napoca, Romania.
J Neurol Sci. 2012 May 15;316(1-2):15-20. doi: 10.1016/j.jns.2012.01.016. Epub 2012 Feb 14.
Impulse control disorders (ICDs) represent an important medical challenge. The authors of the present paper restricted themselves to present an overview of the neurocircuitry that is involved in ICDs and to present information about the mechanisms of neuroplasticity that are the substrate of the ICDs. Understanding the networks involved in ICDs at the level of the cellular and molecular mechanisms of neural and synaptic plasticity may facilitate the understanding of the ways in which various conditions favour the habit formation and compulsivity that are associated with neurological disorders. The psychological, sociological and forensic dimensions of ICDs are beyond the scope of this paper.
冲动控制障碍(ICD)是一个重要的医学挑战。本文作者仅对涉及 ICD 的神经回路进行概述,并提供有关 ICD 基础的神经可塑性机制的信息。了解涉及 ICD 的网络,包括神经和突触可塑性的细胞和分子机制,可能有助于理解各种情况如何促进与神经障碍相关的习惯形成和强迫。本文不涉及 ICD 的心理、社会和法医方面。