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在产妇入院待产时,用胎心监护仪与间断听诊评估胎儿健康状况的对比研究

Cardiotocography versus intermittent auscultation of fetal heart on admission to labour ward for assessment of fetal wellbeing.

作者信息

Devane Declan, Lalor Joan G, Daly Sean, McGuire William, Smith Valerie

机构信息

School of Nursing and Midwifery, National University of Ireland Galway, Galway, Ireland.

出版信息

Cochrane Database Syst Rev. 2012 Feb 15(2):CD005122. doi: 10.1002/14651858.CD005122.pub4.

Abstract

BACKGROUND

The admission cardiotocograph (CTG) is a commonly used screening test consisting of a short (usually 20 minutes) recording of the fetal heart rate (FHR) and uterine activity performed on the mother's admission to the labour ward.

OBJECTIVES

To compare the effects of admission CTG with intermittent auscultation of the FHR on maternal and infant outcomes for pregnant women without risk factors on their admission to the labour ward.

SEARCH METHODS

We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (17 May 2011) (CENTRAL) (The Cochrane Library 2011 Issue 2 of 4), MEDLINE (1966 to 17 May 2011), CINAHL (1982 to 17 May 2011), Dissertation Abstracts (1980 to 17 May 2011) and the reference list of retrieved papers.

SELECTION CRITERIA

All randomised and quasi-randomised trials comparing admission CTG with intermittent auscultation of the FHR for pregnant women between 37 and 42 completed weeks of pregnancy and considered to be at low risk of intrapartum fetal hypoxia and of developing complications during labour.

DATA COLLECTION AND ANALYSIS

Two authors independently assessed trial eligibility and quality, and extracted data. Data were checked for accuracy.

MAIN RESULTS

We included four trials involving more than 13,000 women. All four studies included women in labour. Overall, the studies were at low risk of bias. Although not statistically significant using a strict P < 0.05 criterion, data are consistent with women allocated to admission CTG having, on average, a higher probability of an increase in incidence of caesarean section than women allocated to intermittent auscultation (risk ratio (RR) 1.20, 95% confidence interval (CI) 1.00 to 1.44, four trials, 11,338 women, T² = 0.00, I² = 0%). There was no significant difference in the average treatment effect across included trials between women allocated to admission CTG and women allocated to intermittent auscultation in instrumental vaginal birth (RR 1.10, 95% CI 0.95 to 1.27, four trials, 11,338 women, T² = 0.01, I² = 38%) and fetal and neonatal deaths (RR 1.01, 95% CI 0.30 to 3.47, four trials, 11339 infants, T² = 0.00, I² = 0%).Women allocated to admission CTG had, on average, significantly higher rates of continuous electronic fetal monitoring during labour (RR 1.30, 95% CI 1.14 to 1.48, three trials, 10,753 women, T² = 0.01, I² = 79%) and fetal blood sampling (RR 1.28, 95% CI 1.13 to 1.45, three trials, 10,757 women, T² = 0.00, I² = 0%) than women allocated to intermittent auscultation. There were no differences between groups in other secondary outcome measures.

AUTHORS' CONCLUSIONS: Contrary to continued use in some clinical areas, we found no evidence of benefit for the use of the admission cardiotocograph (CTG) for low-risk women on admission in labour.We found no evidence of benefit for the use of the admission CTG for low-risk women on admission in labour. Furthermore, the probability is that admission CTG increases the caesarean section rate by approximately 20%. The data lacked power to detect possible important differences in perinatal mortality. However, it is unlikely that any trial, or meta-analysis, will be adequately powered to detect such differences. The findings of this review support recommendations that the admission CTG not be used for women who are low risk on admission in labour. Women should be informed that admission CTG is likely associated with an increase in the incidence of caesarean section without evidence of benefit.

摘要

背景

入院时的胎心监护(CTG)是一种常用的筛查测试,包括在母亲进入产房时对胎儿心率(FHR)和子宫活动进行短时间(通常为20分钟)记录。

目的

比较入院时CTG与FHR间歇性听诊对进入产房时无危险因素的孕妇母婴结局的影响。

检索方法

我们检索了Cochrane妊娠与分娩组试验注册库(2011年5月17日)(CENTRAL)(《Cochrane图书馆》2011年第2期,共4期)、MEDLINE(1966年至2011年5月17日)、CINAHL(1982年至2011年5月17日)、《论文摘要》(1980年至2011年5月17日)以及检索到的论文的参考文献列表。

入选标准

所有随机和半随机试验,比较妊娠37至42足周孕妇入院时CTG与FHR间歇性听诊情况,且认为这些孕妇在产时胎儿缺氧及分娩期间发生并发症的风险较低。

数据收集与分析

两位作者独立评估试验的合格性和质量,并提取数据。对数据的准确性进行了核对。

主要结果

我们纳入了四项试验,涉及超过13000名女性。所有四项研究均纳入了分娩期女性。总体而言,这些研究存在偏倚的风险较低。尽管按照严格的P<0.05标准无统计学意义,但数据表明,分配到入院时CTG组的女性剖宫产发生率平均高于分配到间歇性听诊组的女性(风险比(RR)1.20,95%置信区间(CI)1.00至1.44,四项试验,11338名女性,T² = 0.00,I² = 0%)。在器械助产阴道分娩方面,分配到入院时CTG组的女性与分配到间歇性听诊组的女性相比,纳入试验的平均治疗效果无显著差异(RR 1.10,95% CI 0.95至1.27,四项试验,11338名女性,T² = 0.01,I² = 38%),在胎儿及新生儿死亡方面也无显著差异(RR 1.01,95% CI 0.30至3.47,四项试验,11339名婴儿,T² = 0.00,I² = 0%)。分配到入院时CTG组的女性在分娩期间持续电子胎儿监护的平均发生率显著更高(RR 1.30,95% CI 1.14至1.48,三项试验,10753名女性,T² = 0.01,I² = 79%),胎儿血样采集的发生率也显著更高(RR 1.28,95% CI 1.13至1.45,三项试验,10757名女性,T² = 0.00,I² = 0%)。两组在其他次要结局指标上无差异。

作者结论

与一些临床领域仍在继续使用的情况相反,我们未发现入院时对低风险分娩女性使用胎心监护(CTG)有获益的证据。我们未发现入院时对低风险分娩女性使用入院CTG有获益的证据。此外,入院CTG有可能使剖宫产率增加约20%。这些数据缺乏检测围产期死亡率可能存在的重要差异的效力。然而,任何试验或荟萃分析都不太可能有足够的效力检测到此类差异。本综述的结果支持不将入院CTG用于分娩时低风险女性的建议。应告知女性,入院CTG可能会增加剖宫产发生率且无获益证据。

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