BRAMS Laboratory, Department of Psychology, University of Montreal, Canada.
Eur J Pain. 2012 Jul;16(6):870-7. doi: 10.1002/j.1532-2149.2011.00030.x. Epub 2012 Jan 31.
Numerous studies have demonstrated the capacity of music to modulate pain. However, the neurophysiological mechanisms responsible for this phenomenon remain unknown. In order to assess the involvement of descending modulatory mechanisms in the modulation of pain by music, we evaluated the effects of musical excerpts conveying different emotions (pleasant-stimulating, pleasant-relaxing, unpleasant-stimulating) on the spinally mediated nociceptive flexion reflex (or RIII), as well as on pain ratings and skin conductance responses. The RIII reflex and pain ratings were increased during the listening of unpleasant music compared with pleasant music, suggesting the involvement of descending pain-modulatory mechanisms in the effects of musical emotions on pain. There were no significant differences between the pleasant-stimulating and pleasant-relaxing musical condition, indicating that the arousal of music had little influence on pain processing.
大量研究表明音乐具有调节疼痛的能力。然而，负责这一现象的神经生理学机制尚不清楚。为了评估下行调制机制在音乐调节疼痛中的作用，我们评估了传达不同情绪（愉快刺激、愉快放松、不愉快刺激）的音乐片段对脊髓介导的伤害性屈肌反射（或 RIII）的影响，以及对疼痛评分和皮肤电反应的影响。与愉快音乐相比，不愉快音乐的聆听会增加 RIII 反射和疼痛评分，表明下行疼痛调制机制参与了音乐情绪对疼痛的影响。在愉快刺激和愉快放松的音乐条件之间没有显著差异，这表明音乐的唤醒对疼痛处理的影响很小。
