c-MYC and SIRT1 locked in a vicious cycle.
作者信息
Menssen Antje, Hermeking Heiko
出版信息
Oncotarget. 2012 Feb;3(2):112-3. doi: 10.18632/oncotarget.440.
Abstract
摘要
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c-MYC and SIRT1 locked in a vicious cycle.c-MYC与SIRT1陷入恶性循环。
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本文引用的文献
1
The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.c-MYC 癌蛋白、NAMPT 酶、SIRT1 抑制剂 DBC1 和 SIRT1 脱乙酰酶形成正反馈回路。
Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):E187-96. doi: 10.1073/pnas.1105304109. Epub 2011 Dec 21.
2
Sirt1 deacetylates c-Myc and promotes c-Myc/Max association.Sirt1 去乙酰化 c-Myc 并促进 c-Myc/Max 复合物的形成。
Int J Biochem Cell Biol. 2011 Nov;43(11):1573-81. doi: 10.1016/j.biocel.2011.07.006. Epub 2011 Jul 22.
3
SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability.SIRT1 通过涉及 MKP3 和 ERK 对 N-Myc 蛋白稳定性影响的正反馈环促进 N-Myc 癌发生。
PLoS Genet. 2011 Jun;7(6):e1002135. doi: 10.1371/journal.pgen.1002135. Epub 2011 Jun 16.
4
A c-Myc-SIRT1 feedback loop regulates cell growth and transformation.一种c-Myc-SIRT1反馈环调节细胞生长与转化。
J Cell Biol. 2009 Apr 20;185(2):203-11. doi: 10.1083/jcb.200809167. Epub 2009 Apr 13.
5
The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells.由烟酰胺磷酸核糖基转移酶介导的NAD生物合成途径调节哺乳动物细胞中的Sir2活性。
J Biol Chem. 2004 Dec 3;279(49):50754-63. doi: 10.1074/jbc.M408388200. Epub 2004 Sep 20.
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Human Sir2 and the 'silencing' of p53 activity.人类Sir2与p53活性的“沉默”
Trends Cell Biol. 2002 Sep;12(9):404-6. doi: 10.1016/s0962-8924(02)02342-5.
7
Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes.通过基因表达序列分析（SAGE）对c-MYC调控的转录组进行表征：c-MYC靶基因的鉴定与分析。
Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6274-9. doi: 10.1073/pnas.082005599.
8
Mediation of c-Myc-induced apoptosis by p53.p53介导c-Myc诱导的细胞凋亡。
Science. 1994 Sep 30;265(5181):2091-3. doi: 10.1126/science.8091232.
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