Department of Food Science, Penn State University, University Park, Pennsylvania, USA.
J Clin Microbiol. 2012 May;50(5):1748-51. doi: 10.1128/JCM.06185-11. Epub 2012 Feb 15.
Human listeriosis outbreaks in Canada have been predominantly caused by serotype 1/2a isolates with highly similar pulsed-field gel electrophoresis (PFGE) patterns. Multilocus sequence typing (MLST) and multi-virulence-locus sequence typing (MVLST) each identified a diverse population of Listeria monocytogenes isolates, and within that, both methods had congruent subtypes that substantiated a predominant clone (clonal complex 8; virulence type 59; proposed epidemic clone 5 [ECV]) that has been causing human illness across Canada for more than 2 decades.
在加拿大，人类李斯特菌病疫情主要由血清型 1/2a 分离株引起，这些分离株具有高度相似的脉冲场凝胶电泳（PFGE）模式。多位点序列分型（MLST）和多毒力基因座序列分型（MVLST）分别鉴定出李斯特菌属不同的单增李斯特菌分离株群体，其中两种方法都有一致的亚型，证实了一个主要的克隆（克隆复合体 8；毒力型 59；流行克隆 5 [ECV]），该克隆已经在加拿大造成人类疾病超过 20 年。
