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产褥期败血症——仍然是产妇面临的重大威胁。

Puerperal sepsis--still a major threat for parturient.

作者信息

Shamsher Saadia, Rauf Bushara

机构信息

Department of Gynaecology, Khyber Girls Medical College, Peshawar, Pakistan.

出版信息

J Ayub Med Coll Abbottabad. 2010 Jul-Sep;22(3):18-21.

Abstract

BACKGROUND

Puerperal sepsis is one of the leading causes of preventable maternal morbidity and mortality. It is still ranked as 3rd major cause of maternal deaths in our country. The objective of this study was to evaluate morbidity and mortality from puerperal sepsis and to identify its risk factors.

METHODS

This observational study was carried out in Ayub Teaching Hospital over a period of three years. All patients admitted with diagnosis of puerperal sepsis secondary to genital tract infection were evaluated with thorough details of history and examination to determine their demographic details, obstetrical profiles, presenting features, state of infectious morbidity, need for intervention and mortality related to puerperal sepsis.

RESULTS

Puerperal sepsis was 1.7% of all obstetrical admissions and 34.4% of postnatal complications. It was seen common among young patients of 15-25 years age. 61 (66.3%), of lower parity, 58 (63.00%), low socioeconomic status, 60 (65.20%), uneducated patients, 72 (78.20%), home deliveries, 68 (73.90%), prolong labour, 54 (58.60), prolong rupture of membranes from 48-72 hours, 68 (73.8%) and deliveries conducted by untrained birth attendants, 57 (60.5%). Puerperal sepsis morbidity was mostly foul smelling discharge, 23 (25%), retained product of conception, 41 (44.5%), peritonitis, 8 (8.60%), septicaemia, 4 (4.3%), pelvic abscess, 10 (10.80%), endotoxic shock, 4 (4.30%), disseminated intravascular coagulation, 2 (2.1%). Sepsis related mortality was 6/42 (14.2%).

CONCLUSION

Puerperal sepsis is an important public health problem contributing to maternal morbidity and mortality. Majority of predisposing factors are preventable. Optimal antiseptic measures and careful monitoring are needed throughout the process of labour.

摘要

背景

产褥期败血症是可预防的孕产妇发病和死亡的主要原因之一。在我国,它仍然是孕产妇死亡的第三大主要原因。本研究的目的是评估产褥期败血症的发病率和死亡率,并确定其危险因素。

方法

这项观察性研究在阿尤布教学医院进行,为期三年。所有因生殖道感染继发产褥期败血症而入院的患者都接受了详细的病史和检查评估,以确定其人口统计学细节、产科情况、临床表现、感染发病状况、干预需求以及与产褥期败血症相关的死亡率。

结果

产褥期败血症占所有产科入院病例的1.7%,占产后并发症的34.4%。在15至25岁的年轻患者中较为常见。初产次数较低的有61例(66.3%),社会经济地位低的有58例(63.00%),未受过教育的患者有60例(65.20%),在家分娩的有72例(78.20%),产程延长的有68例(73.90%),胎膜破裂延长48至72小时的有54例(58.60%),由未经培训的助产人员接生的有57例(60.5%)。产褥期败血症的发病情况主要为恶臭分泌物23例(25%)、稽留流产41例(44.5%)、腹膜炎8例(8.60%)、败血症4例(4.3%)、盆腔脓肿10例(10.80%)、内毒素休克4例(4.30%)、弥散性血管内凝血2例(2.1%)。败血症相关死亡率为6/42(14.2%)。

结论

产褥期败血症是导致孕产妇发病和死亡的一个重要公共卫生问题。大多数诱发因素是可以预防的。在整个分娩过程中需要采取最佳的防腐措施并进行仔细监测。

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