Fine Morning Hospital and Research Center, Laxminagar, Nagpur, India.
Eur Rev Med Pharmacol Sci. 2012 Jan;16(1):19-24.
Pilonidal disease is a disease of young people, usually men, which can result in an abscess, draining sinus tracts, and moderate debility for some. It probably results from hair penetration beneath the skin, for reasons that are not totally clear. A pilonidal sinus in the sacrococcygeal region is associated with recurrent infection, abscess formation, cellulitis, and fistulae. The infection is usually chronic and non-specific. However, few reports of granulomatous infection like tuberculosis and actinomycosis in pilonidal sinus have been observed. The presentation of tuberculosis in these sinuses may have wide forms, with atypical and uncharacteristic clinical picture, making it difficult to make a diagnosis preoperatively. This paper discusses about pilonidal sinus disease and tubercular infiltration in these sinuses. The diagnosis of tuberculosis in pilonidal sinus disease is elusive, necessitating a high index of suspicion. The literature on the tubercular affliction of pilonidal sinus is scant. Novel diagnostic modalities such as adenosine deaminase levels and polymerase chain reaction (PCR) can be useful in doubtful situations. Physicians should obtain a thorough history focusing on risk behaviors for human immunodeficiency virus infection (HIV) and tuberculosis. Treatment comprises of standard regimen of antitubercular medication and a modest surgical approach towards the sinuses.
藏毛窦疾病是一种青年人疾病，通常发生于男性，可导致脓肿、窦道引流以及部分患者出现中度虚弱。其可能是由于毛发穿透皮肤导致的，但具体原因尚不完全清楚。骶尾部藏毛窦与复发性感染、脓肿形成、蜂窝织炎和瘘管有关。感染通常为慢性且非特异性的。然而，已有少数关于藏毛窦结核和放线菌感染的肉芽肿性感染的报告。这些窦道中的结核表现可能具有广泛的形式，临床表现不典型且无特征性，使得术前诊断变得困难。本文讨论了藏毛窦疾病和窦道内结核浸润。藏毛窦疾病中的结核诊断难以捉摸，需要高度怀疑。关于藏毛窦结核的文献很少。腺苷脱氨酶水平和聚合酶链反应（PCR）等新的诊断方法在可疑情况下可能有用。医生应获取全面的病史，重点关注人类免疫缺陷病毒（HIV）和结核病的感染风险行为。治疗包括标准的抗结核药物治疗和对窦道进行适度的手术治疗。
