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预防化疗与防治被忽视的热带病。

Preventive chemotherapy and the fight against neglected tropical diseases.

机构信息

Department of Control of Neglected Tropical Diseases, World Health Organization, Avenue Appia 20, 1211 Geneva, Switzerland.

出版信息

Expert Rev Anti Infect Ther. 2012 Feb;10(2):237-42. doi: 10.1586/eri.11.165.

DOI:10.1586/eri.11.165
PMID:22339196
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5624510/
Abstract

Preventive chemotherapy is the public health strategy recommended by the WHO against a set of neglected tropical diseases that includes four groups of helminth infections (lymphatic filariasis, onchocerciasis, schistosomiasis and soil-transmitted helminthiasis) and one chlamydial (trachoma) infection. This article presents the characteristics of preventive chemotherapy interventions directed against each disease targeted by this strategy and provides an update on the status of their implementation worldwide.

摘要

预防化疗是世界卫生组织推荐的公共卫生策略,针对一组被忽视的热带病,包括四类蠕虫感染(淋巴丝虫病、盘尾丝虫病、血吸虫病和土源性蠕虫感染)和一种衣原体(沙眼)感染。本文介绍了针对该策略针对的每种疾病的预防化疗干预措施的特点,并提供了全球实施情况的最新信息。

相似文献

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Preventive chemotherapy and the fight against neglected tropical diseases.预防化疗与防治被忽视的热带病。
Expert Rev Anti Infect Ther. 2012 Feb;10(2):237-42. doi: 10.1586/eri.11.165.
2
Summary of global update on preventive chemotherapy implementation in 2016: crossing the billion.2016年全球预防性化疗实施情况最新报告摘要:突破十亿人次。
Wkly Epidemiol Rec. 2017 Oct 6;92(40):589-93.
3
Prospects for the control of neglected tropical diseases by mass drug administration.通过大规模药物给药控制被忽视热带病的前景
Expert Rev Anti Infect Ther. 2009 Feb;7(1):37-56. doi: 10.1586/14787210.7.1.37.
4
Ensuring the timely supply and management of medicines for preventive chemotherapy against neglected tropical diseases.确保用于被忽视热带病预防性化疗的药品的及时供应和管理。
Wkly Epidemiol Rec. 2017 Mar 31;92(13):155-64.
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Compliance with anthelmintic treatment in the neglected tropical diseases control programmes: a systematic review.被忽视热带病控制项目中驱虫治疗的依从性:一项系统综述
Parasit Vectors. 2016 Jan 27;9:29. doi: 10.1186/s13071-016-1311-1.
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Bayesian risk profiling of soil-transmitted helminth infections and estimates of preventive chemotherapy for school-aged children in Côte d'Ivoire.科特迪瓦学龄儿童土壤传播蠕虫感染的贝叶斯风险评估及预防性化疗估计
Parasit Vectors. 2016 Mar 21;9:162. doi: 10.1186/s13071-016-1446-0.
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Baseline Mapping of Neglected Tropical Diseases in Africa: The Accelerated WHO/AFRO Mapping Project.非洲被忽视热带病基线绘图:世界卫生组织/非洲区域办事处加速绘图项目。
Am J Trop Med Hyg. 2021 Apr 26;104(6):2298-2304. doi: 10.4269/ajtmh.20-1538.
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Are current preventive chemotherapy strategies for controlling and eliminating neglected tropical diseases cost-effective?现行的控制和消除被忽视热带病的预防化疗策略是否具有成本效益?
BMJ Glob Health. 2021 Aug;6(8). doi: 10.1136/bmjgh-2021-005456.
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Spatial and temporal distribution of soil-transmitted helminth infection in sub-Saharan Africa: a systematic review and geostatistical meta-analysis.撒哈拉以南非洲土壤传播性蠕虫感染的时空分布:系统评价和地统计学荟萃分析。
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Control of neglected tropical diseases needs a long-term commitment.控制被忽视的热带病需要长期承诺。
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Current state and future directions of interventions for neglected tropical diseases.被忽视热带病干预措施的现状与未来方向
Nat Hum Behav. 2025 Jun 4. doi: 10.1038/s41562-025-02219-0.
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Insights into the epidemiology, pathogenesis, and differential diagnosis of schistosomiasis.血吸虫病的流行病学、发病机制及鉴别诊断研究
Eur J Microbiol Immunol (Bp). 2024 Mar 18;14(2):86-96. doi: 10.1556/1886.2024.00013. Print 2024 May 14.
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Safety Surveillance of Mass Praziquantel and Albendazole Co-Administration in School Children from Southern Ethiopia: An Active Cohort Event Monitoring.

本文引用的文献

1
Preventive chemotherapy in human helminthiasis: theoretical and operational aspects.人体寄生虫病的化学预防:理论与实践
Trans R Soc Trop Med Hyg. 2011 Dec;105(12):683-93. doi: 10.1016/j.trstmh.2011.08.013. Epub 2011 Oct 29.
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Simultaneous administration of praziquantel, ivermectin and albendazole, in a community in rural northern Ghana endemic for schistosomiasis, onchocerciasis and lymphatic filariasis.在加纳北部农村的一个流行血吸虫病、盘尾丝虫病和淋巴丝虫病的社区中,同时给予吡喹酮、伊维菌素和阿苯达唑。
Trop Med Int Health. 2011 Sep;16(9):1112-9. doi: 10.1111/j.1365-3156.2011.02814.x. Epub 2011 Jun 20.
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埃塞俄比亚南部在校儿童群体中吡喹酮与阿苯达唑联合使用的安全性监测:一项动态队列事件监测
J Clin Med. 2022 Oct 26;11(21):6300. doi: 10.3390/jcm11216300.
4
Impact of preventive chemotherapy on transmission of soil-transmitted helminth infections in Pemba Island, United Republic of Tanzania, 1994-2021.坦桑尼亚联合共和国奔巴岛 1994-2021 年预防性化疗对土壤传播性蠕虫感染传播的影响。
PLoS Negl Trop Dis. 2022 Jun 27;16(6):e0010477. doi: 10.1371/journal.pntd.0010477. eCollection 2022 Jun.
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Development and validation of a framework to improve neglected tropical diseases surveillance and response at sub-national levels in Kenya.开发和验证一个框架,以改善肯尼亚国家以下各级的被忽视热带病监测和应对。
PLoS Negl Trop Dis. 2021 Oct 29;15(10):e0009920. doi: 10.1371/journal.pntd.0009920. eCollection 2021 Oct.
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Feasibility of implementing recommendations to improve neglected tropical diseases surveillance and response in Kenya: a modified Delphi study.在肯尼亚实施改进被忽视热带病监测和应对建议的可行性:一项改良德尔菲研究。
BMC Health Serv Res. 2021 Oct 1;21(1):1034. doi: 10.1186/s12913-021-07075-y.
7
In vivo and in vitro efficacy of a single dose of albendazole against hookworm infection in northwest Ethiopia: open-label trial.埃塞俄比亚西北部单剂量阿苯达唑抗钩虫感染的体内和体外疗效:开放标签试验
Trop Med Health. 2021 Mar 20;49(1):25. doi: 10.1186/s41182-021-00308-0.
8
A systematic review and meta-analysis on the rate of human schistosomiasis reinfection.系统评价和荟萃分析人类血吸虫病再感染率。
PLoS One. 2020 Dec 3;15(12):e0243224. doi: 10.1371/journal.pone.0243224. eCollection 2020.
9
Molecular evidence of hybridization between pig and human indicates an interbred species complex infecting humans.分子证据表明猪与人之间存在杂交,表明存在感染人类的杂交种复杂群体。
Elife. 2020 Nov 6;9:e61562. doi: 10.7554/eLife.61562.
10
Schistosomiasis infection in pre-school aged children in Uganda: a qualitative descriptive study to identify routes of exposure.乌干达学龄前儿童血吸虫病感染:定性描述研究以确定暴露途径。
BMC Infect Dis. 2019 Feb 14;19(1):165. doi: 10.1186/s12879-019-3803-z.
A randomised controlled clinical trial on the safety of co-administration of albendazole, ivermectin and praziquantel in infected schoolchildren in Uganda.
在乌干达受感染学童中联合应用阿苯达唑、伊维菌素和吡喹酮的安全性随机对照临床试验。
Trans R Soc Trop Med Hyg. 2011 Apr;105(4):181-8. doi: 10.1016/j.trstmh.2010.11.012. Epub 2011 Feb 25.
4
Integrated implementation of programs targeting neglected tropical diseases through preventive chemotherapy: proving the feasibility at national scale.通过预防性化疗综合实施针对被忽视热带病的方案:在国家范围内证明可行性。
Am J Trop Med Hyg. 2011 Jan;84(1):5-14. doi: 10.4269/ajtmh.2011.10-0411.
5
Lymphatic filariasis and onchocerciasis.淋巴丝虫病和盘尾丝虫病。
Lancet. 2010 Oct 2;376(9747):1175-85. doi: 10.1016/S0140-6736(10)60586-7. Epub 2010 Aug 23.
6
Update on the diagnosis and treatment of food-borne trematode infections.食源性吸虫感染的诊断与治疗进展。
Curr Opin Infect Dis. 2010 Oct;23(5):513-20. doi: 10.1097/QCO.0b013e32833de06a.
7
Spatial co-distribution of neglected tropical diseases in the east African great lakes region: revisiting the justification for integrated control.东非大湖区被忽视热带病的空间分布:重新审视综合控制的合理性。
Trop Med Int Health. 2010 Feb;15(2):198-207. doi: 10.1111/j.1365-3156.2009.02440.x.
8
Epidemiology and control of trachoma: systematic review.沙眼的流行病学和控制:系统评价。
Trop Med Int Health. 2010 Jun;15(6):673-91. doi: 10.1111/j.1365-3156.2010.02521.x. Epub 2010 Apr 4.
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Cost-effectiveness of a successful schistosomiasis control programme in Cambodia (1995-2006).柬埔寨血吸虫病控制规划(1995-2006 年)的成本效益。
Acta Trop. 2010 Mar;113(3):279-84. doi: 10.1016/j.actatropica.2009.11.011. Epub 2009 Dec 3.
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Rescuing the bottom billion through control of neglected tropical diseases.通过控制被忽视的热带病拯救最底层的十亿人。
Lancet. 2009 May 2;373(9674):1570-5. doi: 10.1016/S0140-6736(09)60233-6.