Iranian Center for Endodontic Research, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Acta Odontol Scand. 2013 Jan;71(1):130-6. doi: 10.3109/00016357.2011.654251. Epub 2012 Feb 20.
To conduct a randomized clinical trial to compare the post-operative pain experience as well as clinical and radiographic outcomes of pulpotomy in human permanent molars with irreversible pulpitis using calcium enriched mixture (CEM) cement or mineral trioxide aggregate (MTA).
A total of 413 patients met the inclusion criteria and consented to participate. The patients were randomly allocated into two study arms: MTA pulpotomy (PMTA: n = 208) and CEM pulpotomy (PCEM: n = 205). Numerical rating scale questionnaires were utilized by the patients to record pain intensity (PI) over 7 days post-operatively. The patients were followed-up for 12 months to assess the clinical and radiographic outcomes of treatment. The data was analyzed using Chi-square, Cohen's kappa and t-tests.
There was no significant difference in the mean PI recorded during the 7 post-operative days between the two study arms (p = 0.221). The clinical and radiographic success rates for PMTA at 12-month follow-up were 98 and 95%, respectively; and 97 and 92% for PCEM, respectively. There was no significant differences in clinical (p = 0.7) and radiographic (p = 0.4) success rates between the two arms.
Excellent treatment outcomes occurred in molar teeth with irreversible pulpitis undergoing pulpotomy with MTA and CEM biomaterials.
比较使用钙加强混合物（CEM）水泥或三氧化矿物聚合体（MTA）行恒磨牙不可复性牙髓炎盖髓术后疼痛体验及临床和影像学结果。
共有 413 名符合纳入标准并同意参与的患者。患者被随机分配到两个研究组：MTA 盖髓术（PMTA：n = 208）和 CEM 盖髓术（PCEM：n = 205）。患者使用数字评分量表记录术后 7 天的疼痛强度（PI）。对患者进行为期 12 个月的随访，以评估治疗的临床和影像学结果。使用卡方检验、Cohen's kappa 和 t 检验对数据进行分析。
在术后 7 天的平均 PI 记录中，两组之间没有显著差异（p = 0.221）。PMTA 在 12 个月随访时的临床和影像学成功率分别为 98%和 95%；PCEM 分别为 97%和 92%。两组之间在临床（p = 0.7）和影像学（p = 0.4）成功率方面没有显著差异。
在对患有不可复性牙髓炎的磨牙进行盖髓术时，使用 MTA 和 CEM 生物材料可获得极好的治疗效果。
